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ArticleInternational journal of technology assessment in health care2025

Standards for the conduct and reporting of health technology assessments: Ghana reference case of HTA and economic evaluations.

Richmond Owusu, Brian Adu Asare, Genevieve Cecilia Aryeetey, Ivy Amankwah, Emmanuella Abassah-Konadu, Godwin Gulbi, Saviour Yevutsey, Sergio Torres Rueda, Joseph Kazibwe, Francis Ruiz and 3 more

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Article in International journal of technology assessment in health care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Richmond OwusuSchool of Public Health, University of Ghana, Accra, Ghana.ORCID https://orcid.org/0000-0002-0066-3491
Brian Adu AsareGhana Ministry of Health Technology Assessment Secretariat, Accra, Ghana.ORCID https://orcid.org/0000-0003-2216-501X
Genevieve Cecilia AryeeteySchool of Public Health, University of Ghana, Accra, Ghana.
Ivy AmankwahGhana Ministry of Health Technology Assessment Secretariat, Accra, Ghana.
Emmanuella Abassah-KonaduGhana Ministry of Health Technology Assessment Secretariat, Accra, Ghana.
Godwin GulbiGhana Ministry of Health Technology Assessment Secretariat, Accra, Ghana.
Saviour YevutseyGhana Ministry of Health Technology Assessment Secretariat, Accra, Ghana.
Sergio Torres RuedaLondon School of Hygiene and Tropical Medicine, London, UK.
Joseph KazibweLondon School of Hygiene and Tropical Medicine, London, UK.ORCID https://orcid.org/0000-0002-8315-1503
Francis RuizLondon School of Hygiene and Tropical Medicine, London, UK.ORCID https://orcid.org/0000-0001-5183-3959
Joycelyn ZeezGhana Ministry of Health Technology Assessment Secretariat, Accra, Ghana.
Ghana Health Technology Assessment Technical Working Group
Justice NonvignonSchool of Public Health, University of Ghana, Accra, Ghana.ORCID https://orcid.org/0000-0002-7484-9491

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe methods of economic evaluation and HTA should be based on best practices and standards, tailored to unique country contexts that can be systematically applied to inform decisions. This paper outlines standards for the conduct of economic evaluations for HTA in Ghana.

methodsA five-step process was followed to develop the HTA reference case as a methodological and reporting benchmark. These include (a) a review of literature and evidence synthesis, (b) a review of country policies, (c) a review and adaption of international frameworks, (d) expert/stakeholder consultations, and (e) the development of a methodological framework. A series of stakeholder consultations were done to refine, finalize, and validate the outcomes of the processes to generate a finalized reference case.

resultsThe Ghana reference case is made up of 14 components comprising: evidence synthesis, evaluation type, perspectives on cost, perspectives of outcomes, choice of comparator, data sources, outcome measures, discount rate, uncertainty, equity considerations, time horizon, heterogeneity, transparency, and budget impact. These provide methodological considerations and reporting requirements for economic evaluations for HTA. It provides a framework to ensure the best research methods are adopted to harmonize the evidence-generation process with the expectations of policy and decision-makers and ensure that policy decisions are based on uniform evidence.

conclusionRecommendations set out in this reference case when followed can provide context-specific evidence to support a rigorous and transparent system for evaluating healthcare interventions and technologies. It will support decision-making, ultimately improving the quality and efficiency of healthcare delivery in the country.

Indexed as

Technology Assessment, BiomedicalCost-Benefit AnalysisGhanaHealth PolicyHumansResearch Designeconomic evaluationGhanahealth technology assessmentreference case

Identifiers

PMID40026051
PMCPMC11950332

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