Evidence map›Paper›PMID 40025845›Full record

SynthesisClinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery2025

Systematic Review and Meta-Analysis of Audiometric Parameters for Assistive Hearing Technology for Adults and Children With Tympanic Membrane Perforation.

Thomas Hampton, Alan Sanderson, Kevin Mortimer, Mahmood Bhutta

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thomas HamptonDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.
Alan SandersonBrighton & Sussex Medical School, Brighton, UK.
Kevin MortimerCambridge Africa, University of Cambridge, Cambridge, UK.
Mahmood BhuttaBrighton & Sussex Medical School, Brighton, UK.

Funding

TWJ FoundationWellcome TrustWellcome Trust 203919/Z/16/Z
6 · The paper itself

Abstract

introductionTympanic membrane perforation can cause hearing impairment with detrimental effects on communication and quality of life, and is a problem affecting an estimated 250 million people. To date, there is little analysis to inform public policy on options for assistive hearing technology rehabilitation in this group.

methodsWe undertook a systematic review and meta-analysis of six electronic databases registered with PROSPERO and reported in accordance with PRISMA 2020 standards. The primary outcome was the mean air and bone conduction hearing threshold associated with tympanic perforation.

resultsOf 720 studies identified, 16 contained data for meta-analysis. Mean air conduction threshold was 48.3 dB HL in adults and 31.9 dB HL in children. Mean bone conduction was 26.6 dB HL in adults and 9.5 dB HL in children. The prediction interval was -1.7 to 46.7 dB HL for bone conduction and 15.0-70.5 dB HL for air conduction.

conclusionsThe majority of adults and children with tympanic perforation have air conduction thresholds within the range of rehabilitation with air conduction hearing aids. The majority also have good sensorineural hearing reserve, meaning bone conduction devices are also suitable. Our analysis can guide the development of affordable technology for the rehabilitation of those with tympanic perforation.

Indexed as

AudiometryHearing AidsTympanic Membrane PerforationAdultAuditory ThresholdBone ConductionChildHumans

Identifiers

PMID40025845
PMCPMC12128012

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