Evidence map›Paper›PMID 40025464›Full record

ArticleBMC oral health2025

Data-driven AI platform for dens evaginatus detection on orthodontic intraoral photographs.

Ruiyang Ren, Jialing Liu, Shihao Li, Xiaoyue Wu, Xingchen Peng, Wen Liao, Zhihe Zhao

Abstract read
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ruiyang Ren *State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, China.
Jialing Liu *State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, China.
Shihao LiDepartment of Biotherapy, Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
Xiaoyue WuState Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, China.
Xingchen PengDepartment of Biotherapy, Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
Wen LiaoState Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, China. liaowenssw@126.com.
Zhihe ZhaoState Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, China. zhzhao@scu.edu.cn.

Funding

Chengdu Artificial Intelligence Applications and Development Industrial Technology Basic Public Service Platform 2021-0166-1-2IOF Young Grants 2022Y08Major project of Sichuan Science and Technology Department 2022ZDZX0031Natural Science Foundation of Sichuan Province 2023NSFSC0562the central government guides the construction of local S&T innovation funds 2021ZYD104the College Students' Innovative Entrepreneurial Training Plan Program S202310610252
6 · The paper itself

Abstract

backgroundThe aim of our study was to develop and evaluate a deep learning model (BiStageNet) for automatic detection of dens evaginatus (DE) premolars on orthodontic intraoral photographs. Additionally, based on the training results, we developed a DE detection platform for orthodontic clinical applications.

methodsWe manually selected the premolar areas for automatic premolar recognition training using a dataset of 1,400 high-quality intraoral photographs. Next, we labeled each premolar for DE detection training using a dataset of 2,128 images. We introduced the Dice coefficient, accuracy, sensitivity, specificity, F1-score, ROC curve as well as areas under the ROC curve to evaluate the learning results of our model. Finally, we constructed an automatic DE detection platform based on our trained model (BiStageNet) using Pytorch.

resultsOur DE detection platform achieved a mean Dice coefficient of 0.961 in premolar recognition, with a diagnostic accuracy of 85.0%, sensitivity of 88.0%, specificity of 82.0%, F1 Score of 0.854, and AUC of 0.93. Experimental results revealed that dental interns, when manually identifying DE, showed low specificity. With the tool's assistance, specificity significantly improved for all interns, effectively reducing false positives without sacrificing sensitivity. This led to enhanced diagnostic precision, evidenced by improved PPV, NPV, and F1-Scores.

conclusionOur BiStageNet was capable of recognizing premolars and detecting DE with high accuracy on intraoral photographs. On top of that, our self-developed DE detection platform was promising for clinical application and promotion.

Indexed as

BicuspidDeep LearningDens in DentePhotography, DentalHumansSensitivity and SpecificityArtificial intelligenceDeep learningMedical image classificationOrthodontic intraoral image

Identifiers

PMID40025464
PMCPMC11872327

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.