Evidence map›Paper›PMID 40025458›Full record

Trial reportBMC anesthesiology2025

Efficacy and safety of ciprofol for gastroscopy in patients with obesity: a randomised clinical controlled trial using different weight-based dosing scales.

Danru Xie, Yanjing Zhang, Feifei Li, Yaoheng Yang, Mengjiao Che, Geng Li, Yiwen Zhang

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Danru Xie *Department of Anaesthesiology, Shunde Hospital of Southern Medical University The First People's Hospital, Shunde District, Foshan City, Foshan, 528308, China.
Yanjing Zhang *Department of Anaesthesiology, Shunde Hospital of Southern Medical University The First People's Hospital, Shunde District, Foshan City, Foshan, 528308, China.
Feifei LiDepartment of Anaesthesiology, Shunde Hospital of Southern Medical University The First People's Hospital, Shunde District, Foshan City, Foshan, 528308, China.
Yaoheng YangDepartment of Anaesthesiology, Shunde Hospital of Southern Medical University The First People's Hospital, Shunde District, Foshan City, Foshan, 528308, China.
Mengjiao CheDepartment of Anaesthesiology, Shunde Hospital of Southern Medical University The First People's Hospital, Shunde District, Foshan City, Foshan, 528308, China.
Geng LiDepartment of Anaesthesiology, Shunde Hospital of Southern Medical University The First People's Hospital, Shunde District, Foshan City, Foshan, 528308, China.
Yiwen ZhangDepartment of Anaesthesiology, Shunde Hospital of Southern Medical University The First People's Hospital, Shunde District, Foshan City, Foshan, 528308, China. ssss047@163.com.

Funding

the 2021 Key Specialist Project of Clinical Medicine, Shunde Hospital of Southern Medical University (Cultivation Project) SRSP2021039the 2023 Basic and Applied Basic Research Joint Fund in Guangdong Province (Guangdong-Foshan) 2023A1515140142the 2023 Key Scientific Research Platforms and Projects of Ordinary Universities in Guangdong Province 2023ZDZX2008
6 · The paper itself

Abstract

backgroundThis study aimed to compare the efficacy and safety of ciprofol-induced doses based on three indices: total body weight (TBW), ideal body weight (IBW), and lean body weight (LBW) in patients with obesity undergoing gastroscopy.

methodsIn a single-centre, prospective, randomised study conducted at an endoscopy centre, a total of 108 patients aged 18-65 years who underwent painless gastroscopy and had a body mass index (BMI) of 28-39.9 kg/m

conclusionsInduction doses of ciprofol based on TBW or IBW provided better anaesthesia than doses based on LBW for gastroscopy in patients with obesity. LBW-based induction doses of ciprofol improved cardiovascular stability and respiratory safety, whereas IBW-based induction doses of ciprofol reduced respiratory depression.

trial registrationThis study was registered in the Chinese Clinical Trial Registry (ChiCTR2300073539 first registration date 13/07/2023).

Indexed as

Body WeightGastroscopyObesityAdolescentAdultAgedBody Mass IndexCyclopropanesDose-Response Relationship, DrugFemaleHumansMaleMiddle AgedProspective StudiesYoung Adult(2-(1R)-1-cyclopropyl)ethyl-6-isopropyl-phenolCyclopropanesCiprofolGastroscopyObesityWeight-based scalars

Identifiers

PMID40025458
PMCPMC11874440

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.