ArticleAdvances in therapy2025
Characterizing Patient Diversity via Healthcare Access Determinants: A New Approach for Measuring Improvements in Clinical Trial Diversity in the United States.
Article in Advances in therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Patient Preferences for Neuromyelitis Optica Spectrum Disorder (NMOSD) Treatments: Results from a Discrete Choice Experiment Study in the USA.The patient · 2026Article
- Connecting Innovation and Trust through Translational Sciences - A Need for a Community Focus and Effective Education Strategiess.Puerto Rico health sciences journal · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionRacial and ethnic minorities are frequently under-represented in biomedical research in the United States (US), and the under-representation is amplified in clinical trials in patients with rare diseases. The REthinking MeAsures of DivErsity (REMADE) study was conducted to develop and test a set of questions that may more accurately capture the diversity of patients via socioeconomic, cultural, and ethnic parameters.
methodsA web-based survey was developed to assess race, ethnicity/culture, socioeconomic status, disability/mobility, and transportation issues. The survey responses included 5 racial categories as well as 17 cultures, heritages, and/or ethnicities and were multiselect. The survey was tested in US adults from under-represented populations. Survey results were compared with data collected with a pre-survey intake form (PSIF) that utilized historical categories for race and ethnicity.
resultsOf 219 total survey respondents, 59.8% (131/219) were assigned female sex at birth and 51.1% (112/219) were aged ≥ 18 to < 30 years. Respondents reported being predominantly Black [77.3% [163/211)] or white [19.0% (40/211)] in the PSIF. When respondents were allowed to assign percentages across multiple categories in the survey, only 34.2% (75/219) and 10.5% (23/219) identified as 100% Black or white, respectively. As with race, the REMADE ethnicity/cultural categories revealed greater diversity in the respondent population.
conclusionsThe REMADE survey results suggest that race and cultural identity are more multidimensional than historical questions/categories were able to capture. These insights, along with those generated on socioeconomic, disability, and transportation issues, will guide initiatives to support fair and equitable representation in clinical trials.
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