Observational studyObesity surgery2025
Impact of BMI Reduction After Sleeve Surgery on ESR and CRP Levels in Patients with Obesity.
Observational study in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07655739 (Temporal Changes in Fractalkine), which is not on this map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Temporal Changes in Fractalkine (CX3CL1) Levels Following Sleeve Gastrectomy and Their Association With Weight Loss: A Prospective Study
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObesity is commonly linked with a pro-inflammatory condition, marked by elevated levels of inflammatory biomarkers such as C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR). Sleeve gastrectomy, a widely utilized bariatric procedure, aims to achieve substantial weight loss and enhance metabolic function. This study aims to examine the impact of body mass index (BMI) reduction following sleeve gastrectomy on the levels of inflammatory markers CRP and ESR in obese individuals.
methodsA prospective observational study was carried out on patients with obesity who underwent sleeve gastrectomy between 2020 and 2022 at Luqman Hakim Medical Education Center. CRP and ESR levels were recorded preoperatively and then at 6- and 12-month post-surgery. Simple regression analysis was employed to evaluate the correlation between BMI reduction and changes in CRP and ESR levels over time.
resultsA significant reduction in BMI, CRP, and ESR levels was observed at both 6- and 12-month post-surgery. However, regression analysis indicated that BMI reduction did not significantly predict changes in ESR (B = 0.209, p = 0.262) or CRP (B = 0.274, p = 0.079) at the 6-month and 12-month follow-ups (CRP: B = 0.123, p = 0.138; ESR: B = 0.122, p = 0.453).
conclusionsWhile sleeve gastrectomy significantly reduces BMI and inflammatory markers such as CRP and ESR in patients with obesity, the direct association between BMI reduction and these markers was not statistically significant. Further studies are warranted to elucidate the underlying mechanisms and identify other potential predictors of inflammatory marker reduction post-surgery.
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Registered trials
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