Evidence map›Paper›PMID 40025285›Full record

ArticleNPJ digital medicine2025

Developing a named entity framework for thyroid cancer staging and risk level classification using large language models.

Matrix M H Fung, Eric H M Tang, Tingting Wu, Yan Luk, Ivan C H Au, Xiaodong Liu, Victor H F Lee, Chun Ka Wong, Zhili Wei, Wing Yiu Cheng and 8 more

Registry-linked trialAbstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07234539 (A Randomized Controlled Trial to Evaluate an Artificial Intelligence-enabled Clinical Assistant Leveraging Large Language Models for Thyroid Cancer Staging and Risk Stratification Among Medical Students and Clinicians), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07234539 naenrolling by invitationnot on this map

A Randomized Controlled Trial to Evaluate an Artificial Intelligence-enabled Clinical Assistant Leveraging Large Language Models for Thyroid Cancer Staging and Risk Stratification Among Medical Students and Clinicians

TypeinterventionalSponsorThe University of Hong KongRan2025 to 2027Enrolled76ConditionsThyroid Cancer, Large Language ModelsArmsAI-enabled clinical assistant
3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Matrix M H Fung *Division of Endocrine Surgery, Department of Surgery, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Eric H M Tang *Laboratory of Data Discovery for Health (D²4H), Hong Kong Science Park, Hong Kong SAR, China.
Tingting Wu *Laboratory of Data Discovery for Health (D²4H), Hong Kong Science Park, Hong Kong SAR, China.
Yan LukDivision of Endocrine Surgery, Department of Surgery, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Ivan C H AuSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Xiaodong LiuDivision of Endocrine Surgery, Department of Surgery, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Victor H F LeeDepartment of Clinical Oncology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Chun Ka WongDepartment of Medicine, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Zhili WeiLaboratory of Data Discovery for Health (D²4H), Hong Kong Science Park, Hong Kong SAR, China.
Wing Yiu ChengLaboratory of Data Discovery for Health (D²4H), Hong Kong Science Park, Hong Kong SAR, China.
Isaac C Y TaiDepartment of Orthopaedics and Traumatology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Joshua W K HoLaboratory of Data Discovery for Health (D²4H), Hong Kong Science Park, Hong Kong SAR, China.
Jason W H WongSchool of Biomedical Science, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Brian H H LangDivision of Endocrine Surgery, Department of Surgery, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Kathy S M LeungLaboratory of Data Discovery for Health (D²4H), Hong Kong Science Park, Hong Kong SAR, China.
Zoie S Y WongThe Kirby Institute, University of New South Wales, Sydney, Australia.
Joseph T WuLaboratory of Data Discovery for Health (D²4H), Hong Kong Science Park, Hong Kong SAR, China. joewu@hku.hk.
Carlos K H WongLaboratory of Data Discovery for Health (D²4H), Hong Kong Science Park, Hong Kong SAR, China. carlosho@hku.hk.

Funding

Innovation and Technology Commission AIR@InnoHK
6 · The paper itself

Abstract

We developed a named entity (NE) framework for information extraction from semi-structured clinical notes retrieved from The Cancer Genome Atlas-Thyroid Cancer (TCGA-THCA) database and examined Large Language Models (LLMs) strategies to classify the 8

Identifiers

PMID40025285
PMCPMC11873034

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.