Evidence map›Paper›PMID 40025052›Full record

ArticleScientific reports2025

Sensory processing sensitivity in adult dental patients and its relation to perceived stress, cortisol, and serotonin secretion.

Krystyna Golonka, Bożena Gulla, Dorota Kościelniak, Dagmara Darczuk, Beata Cienkosz-Stepanczak, Beata Bystrowska, Dominika Fortuna, Tamas Kozicz, Wirginia Krzyściak

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Krystyna GolonkaInstitute of Applied Psychology, Faculty of Management and Social Communication, Jagiellonian University, 30-348, Kraków, Poland. krystyna.golonka@uj.edu.pl.
Bożena GullaInstitute of Applied Psychology, Faculty of Management and Social Communication, Jagiellonian University, 30-348, Kraków, Poland.
Dorota KościelniakDepartment of Developmental Dentistry, Institute of Dentistry, Jagiellonian University Medical College, 31-155, Kraków, Poland.
Dagmara DarczukDepartment of Periodontology, Prophylaxis and Oral Medicine, Institute of Dentistry, Jagiellonian University Medical College, 31-155, Kraków, Poland.
Beata Cienkosz-StepanczakLaboratory of Anthropology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Kraków, 30-387, Poland.
Beata BystrowskaDepartment of Toxicology, Faculty of Pharmacy, Jagiellonian University Medical College, 30-688, Kraków, Poland.
Dominika FortunaDoctoral School in the Social Sciences, Jagiellonian University, 31-010, Kraków, Poland.
Tamas KoziczDepartment of Genetics and Genomic Sciences, Icahn School of Medicine, Mount Sinai, New York, NY, 10029, USA.
Wirginia KrzyściakDepartment of Medical Diagnostics, Faculty of Pharmacy, Jagiellonian University Medical College, 30-688, Kraków, Poland.

Funding

Jagiellonian University, Kraków, Poland U1U/P02/NO/02.85
6 · The paper itself

Abstract

Sensory processing sensitivity (SPS) is a biologically determined trait that influences how individuals respond to external and internal stimuli. A high level of SPS is characterized by three factors: increased emotional reactivity, heightened sensitivity to subtle stimuli, and greater susceptibility to overstimulation, all of which may impact well-being and health. This study examined the relationships between SPS, perceived stress, affect, and biochemical responses in adult dental patients (N = 157) on the day of a routine dental visit. Biochemical measures included morning cortisol and serotonin secretion (saliva samples), and cortisol concentration accumulated in recent months (hair sample). Perceived stress and negative and positive affect were assessed while patients waited for a dental procedure. The correlation analysis revealed that higher SPS level was associated with elevated hair cortisol and more negative affect. Cluster analyses tested SPS and its factors independently, revealing that individuals with higher SPS had higher cortisol levels in saliva and hair samples, as well as greater perceived stress and negative affect. Salivary serotonin levels showed varied relationships with different SPS factors, indicating the need to analyze SPS as a multidimensional construct. The results indicate that increased hair and salivary cortisol may be considered as biomarkers of SPS. In the context of patient-centered care, considering SPS levels may contribute to enhanced motivation for regular dental visits and improved treatment adherence.

Indexed as

HydrocortisoneSerotoninStress, PsychologicalAdultAgedBiomarkersFemaleHairHumansMaleMiddle AgedSalivaYoung AdultBiomarkersHydrocortisoneSerotoninCortisolDental treatmentSensory processing sensitivitySerotoninStress

Identifiers

PMID40025052
PMCPMC11873274

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.