Evidence map›Paper›PMID 40025040›Full record

ArticleScientific data2025

A dataset on formulation parameters and characteristics of drug-loaded PLGA microparticles.

Zeqing Bao, Jongwhi Kim, Candice Kwok, Frantz Le Devedec, Christine Allen

Abstract readDataset
In one paragraph

Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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  10. MakingInternational journal of pharmaceutics: X · 2025
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  14. Machine Learning for Predicting Drug Release Behavior of PLGA Microspheres.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zeqing BaoLeslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, M5S 3M2, Canada.
Jongwhi KimLeslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, M5S 3M2, Canada.
Candice KwokLeslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, M5S 3M2, Canada.
Frantz Le DevedecAcceleration Consortium, Toronto, ON, M5S 3H6, Canada.
Christine AllenLeslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, M5S 3M2, Canada. cj.allen@utoronto.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polymer microparticles (MPs) are widely used to create long-acting injectable formulations due to their ability to enable sustained drug release. This feature can significantly benefit chronic disease management by reducing dosing frequency and improving patient adherence. To support the design and development of polymer MPs, we have compiled a dataset on MPs formed from poly(lactide-co-glycolide) (PLGA), the most commonly used polymer in commercial MP drug products. This dataset, derived from the literature, covers 321 in vitro release studies involving 89 different drugs. It aims to streamline future MP development by providing a reference for the current PLGA MP design space and supporting data-driven approaches such as machine learning. Published with open access, this dataset encourages broad utilization and aims to expand the range of available MP formulations.

Indexed as

Polylactic Acid-Polyglycolic Acid CopolymerDelayed-Action PreparationsDrug CompoundingDrug LiberationMicrospheresDelayed-Action PreparationsPolylactic Acid-Polyglycolic Acid Copolymer

Identifiers

PMID40025040
PMCPMC11873201

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.