Evidence map›Paper›PMID 40025024›Full record

ArticleNature communications2025

In situ valence-transited arsenic nanosheets for multi-modal therapy of colorectal cancer.

Hongyue Zheng, Ke Zhang, Jigang Piao, Chaofeng Mu, Xiaowei Xie, Mengying Cheng, Tianxiang Yue, Jiang Sun, Bin Li, Yinghui Wei and 4 more

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Hongyue Zheng *Libraries of Zhejiang Chinese Medical University, Zhejiang Chinese Medical University, Hangzhou, China. zhy@zcmu.edu.cn.
Ke Zhang *School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Jigang PiaoSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Chaofeng MuSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Xiaowei XieSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Mengying ChengSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Tianxiang YueSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Jiang SunSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Bin LiSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Yinghui WeiSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Hangsheng ZhengSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Lai JiangSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Douae Nihed HabiballahSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Fanzhu LiSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China. lifanzhu@zcmu.edu.cn.

Funding

National Natural Science Foundation of China (National Science Foundation of China) No.81873014National Natural Science Foundation of China (National Science Foundation of China) NO.82374048
6 · The paper itself

Abstract

Late-stage and advanced colorectal cancer (CRC) often prove to be resistant to current treatment regimens, due to the evolving tumor microenvironment. Chemotherapy-dominated multi-modal therapeutic strategies based on the specific CRC microenvironment open a new horizon for eradicating colorectal tumors. Here, in situ valence-transited arsenic nanosheets are developed as a multi-modal therapeutic platform by responding to the H

Indexed as

Antineoplastic AgentsArsenicColorectal NeoplasmsNanoparticlesNanostructuresAnimalsCell Line, TumorCombined Modality TherapyCopperHumansMiceMice, Inbred BALB CPolyethylene GlycolsTumor MicroenvironmentXenograft Model Antitumor AssaysAntineoplastic AgentsArsenicCopperPolyethylene Glycols

Identifiers

PMID40025024
PMCPMC11873056

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.