Evidence map›Paper›PMID 40024991›Full record

ArticleClinical journal of gastroenterology2025

A case of relapsed pan-colonic ulcerative colitis accompanied with gastroduodenal lesions immediately after COVID-19.

Katsuya Endo, Tomonori Satoh, Yuki Yoshino, Shiho Kondo, Yoko Kawakami, Daisuke Fukushi, Atsuko Takasu, Takayuki Kogure, Morihisa Hirota, Kennichi Satoh

Abstract readCase Reports
In one paragraph

Article in Clinical journal of gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. A Rare Case of Small Bowel Ulceration Induced by COVID-19.Journal of inflammation research · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Katsuya EndoDivision of Gastroenterology, Tohoku Medical and Pharmaceutical University School of Medicine, 1-15-1 Fukumuro, Miyagino-ku, Sendai, Miyagi, 983-8536, Japan. kendo@tohoku-mpu.ac.jp.ORCID http://orcid.org/0000-0002-6449-8392
Tomonori SatohDivision of Gastroenterology, Tohoku Medical and Pharmaceutical University School of Medicine, 1-15-1 Fukumuro, Miyagino-ku, Sendai, Miyagi, 983-8536, Japan.
Yuki YoshinoDivision of Gastroenterology, Tohoku Medical and Pharmaceutical University School of Medicine, 1-15-1 Fukumuro, Miyagino-ku, Sendai, Miyagi, 983-8536, Japan.
Shiho KondoDivision of Gastroenterology, Tohoku Medical and Pharmaceutical University School of Medicine, 1-15-1 Fukumuro, Miyagino-ku, Sendai, Miyagi, 983-8536, Japan.
Yoko KawakamiDivision of Gastroenterology, Tohoku Medical and Pharmaceutical University School of Medicine, 1-15-1 Fukumuro, Miyagino-ku, Sendai, Miyagi, 983-8536, Japan.
Daisuke FukushiDivision of Gastroenterology, Tohoku Medical and Pharmaceutical University School of Medicine, 1-15-1 Fukumuro, Miyagino-ku, Sendai, Miyagi, 983-8536, Japan.
Atsuko TakasuDivision of Gastroenterology, Tohoku Medical and Pharmaceutical University School of Medicine, 1-15-1 Fukumuro, Miyagino-ku, Sendai, Miyagi, 983-8536, Japan.
Takayuki KogureDivision of Gastroenterology, Tohoku Medical and Pharmaceutical University School of Medicine, 1-15-1 Fukumuro, Miyagino-ku, Sendai, Miyagi, 983-8536, Japan.
Morihisa HirotaDivision of Gastroenterology, Tohoku Medical and Pharmaceutical University School of Medicine, 1-15-1 Fukumuro, Miyagino-ku, Sendai, Miyagi, 983-8536, Japan.
Kennichi SatohDivision of Gastroenterology, Tohoku Medical and Pharmaceutical University School of Medicine, 1-15-1 Fukumuro, Miyagino-ku, Sendai, Miyagi, 983-8536, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some patients with ulcerative colitis (UC) suffer from complicated UC-associated upper gastrointestinal lesions. However, the trigger of these lesions has not been clarified. Herein, we present a 28-year-old man with relapsed pan-colonic UC accompanied by gastroduodenal lesions immediately after contracting coronavirus disease 2019 (COVID-19). In this patient, UC relapsed approximately 7 days after the COVID-19 onset, despite being in remission for 3 years. The patient also developed symptoms such as epigastric pain and nausea on day 19 of COVID-19. The endoscopic and pathologic findings of the stomach and duodenum closely resembled colorectal lesions of UC; accordingly, we diagnosed the patient with UC-associated gastroduodenal lesions. Corticosteroids were significantly effective in the colorectal and upper gastrointestinal lesions, leading to remission. This report is the first to describe UC-associated upper GI lesions that developed right after COVID-19 infection. Therefore, COVID-19 can be a possible trigger of UC-associated upper gastrointestinal lesion. Further studies are needed to understand the relationship between the onset of UC or UC-associated upper GI lesions and COVID-19.

Indexed as

Colitis, UlcerativeCOVID-19AdultHumansMaleRecurrenceSARS-CoV-2COVID-19UC-associated gastroduodenal lesionUlcerative colitis

Identifiers

PMID40024991
PMCPMC12095360

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.