Evidence map›Paper›PMID 40024977›Full record

ArticleMikrochimica acta2025

Sensitive colorimetric sensing of dopamine and TYR based on enhanced HRP-like activity of CuNi/Fe LDHs nanozymes.

Fenghua Geng, Min Huang, Xiaoli Zhang, Yongxiang Wang, Congying Shao, Maotian Xu

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Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Fenghua Geng *Henan Key Laboratory of Biomolecular Recognition and Sensing, Henan Joint International Research Laboratory of Chemo/Biosensing and Early Diagnosis of Major Diseases, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu, 476000, China.
Min Huang *Key Laboratory of Green and Precise Synthetic Chemistry and Applications, Ministry of Education, College of Chemistry and Material Science, Huaibei Normal University, Huaibei, 235000, China.
Xiaoli ZhangHenan Key Laboratory of Biomolecular Recognition and Sensing, Henan Joint International Research Laboratory of Chemo/Biosensing and Early Diagnosis of Major Diseases, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu, 476000, China.
Yongxiang WangKey Laboratory of Green and Precise Synthetic Chemistry and Applications, Ministry of Education, College of Chemistry and Material Science, Huaibei Normal University, Huaibei, 235000, China. wangyx2006@pku.edu.cn.
Congying ShaoKey Laboratory of Green and Precise Synthetic Chemistry and Applications, Ministry of Education, College of Chemistry and Material Science, Huaibei Normal University, Huaibei, 235000, China.
Maotian XuHenan Key Laboratory of Biomolecular Recognition and Sensing, Henan Joint International Research Laboratory of Chemo/Biosensing and Early Diagnosis of Major Diseases, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu, 476000, China.

Funding

Innovation Scientists and Technicians Troop Construction Projects of Henan Province 41National Natural Science Foundation of China 21575087National Natural Science Foundation of China 22474072Startup Initiative Foundation from Huaibei Normal University 15601215Startup Initiative Foundation from Shangqiu Normal University 7001143
6 · The paper itself

Abstract

CuNi/Fe LDHs with HRP-like activity (nanozyme) have been prepared. Contrary to the expected design, free dopamine (DA) was found to greatly enhance the catalytic performances of CuNi/Fe LDHs nanozyme. As far as we know, this is the first report that free DA boosts the catalytic performances of LDHs. Given the superior HRP-like enzyme activity of DA-CuNi/Fe LDHs, a colorimetric method for DA and tyrosinase (TYR) assay with high sensitivity and specificity was established, and it was successfully applied to quantify DA in artificial cerebrospinal fluid and TYR in newborn calf serum. The acquired insights in DA-CuNi/Fe LDHs will contribute to future rational design of other high-performance nanozymes. In addition, the novel DA and TYR assay pave a way for designing further nanozymes-based colorimetric chemo/biosensors.

Indexed as

ColorimetryDopamineMonophenol MonooxygenaseTyrosineAnimalsBiosensing TechniquesCatalysisCattleIronLimit of DetectionDopamineIronMonophenol MonooxygenaseTyrosineColorimetryDopamineLayered double hydroxidesNanozymeTyrosinase

Identifiers

PMID40024977

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