Evidence map›Paper›PMID 40024811›Full record

ArticleInternational journal of gynecological cancer : official journal of the International Gynecological Cancer Society2025

Assessment of readability of gynecologic cancer clinical trials literature at National Cancer Institute-designated Comprehensive Cancer Centers.

Julia Chalif, Wafa Khadraoui, John L Hays, Larry J Copeland, Roberto Vargas, David M O'Malley, Laura M Chambers

Abstract read
In one paragraph

Article in International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Julia ChalifThe Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute, Division of Gynecologic Oncology, Columbus, OH, USA.
Wafa KhadraouiThe Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute, Division of Gynecologic Oncology, Columbus, OH, USA.
John L HaysThe Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute, Division of Gynecologic Oncology, Columbus, OH, USA.
Larry J CopelandThe Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute, Division of Gynecologic Oncology, Columbus, OH, USA.
Roberto VargasThe Cleveland Clinic, Division of Gynecologic Oncology, Cleveland, OH, USA.
David M O'MalleyThe Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute, Division of Gynecologic Oncology, Columbus, OH, USA.
Laura M ChambersThe Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute, Division of Gynecologic Oncology, Columbus, OH, USA. Electronic address: laura.chambers@osumc.edu.

Funding

The Ohio State University Center for clinical and Translational ScienceUL1TR001070 · NCATS · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2013 to 2017
$22.6M
Translational Training Grant in Experimental TherapeuticsK12CA133250 · NCI · OHIO STATE UNIVERSITY · PI WILLIAM E. CARSON, Rosa Lapalombella · 2008 to 2026
$15.0M
Advanced Research Training in Immunology for Surgery Trainees (ARTIST)T32AI106704 · NIAID · OHIO STATE UNIVERSITY · PI GINNY L BUMGARDNER, Jon R Wisler · 2014 to 2026
$3.5M
NCATS NIH HHS UL1 TR001070NCI NIH HHS K12 CA133250NIAID NIH HHS T32 AI106704
6 · The paper itself

Abstract

objectiveThis study aimed to assess the readability of patient-facing gynecologic cancer clinical trial information on National Cancer Institute-Designated Comprehensive Cancer Center (NCI-CCCs) websites.

methodsThis was a cross-sectional analysis of publicly accessible information pertaining to gynecologic cancer clinical trials on NCI-CCC's websites in September 2023. Clinical trial descriptions for endometrial, cervical, and ovarian cancers were assessed. Websites with limited to no descriptive information regarding their clinical trials were excluded. Readability was assessed using Readability Studio Professional Edition software for 5 readability metrics (FORCAST, Fry, Gunning Fog, Raygor Estimate, and SMOG).

resultsOf 56 NCI-CCCs evaluated, 78% (n = 44) had information pertaining to gynecologic cancer clinical trials and gynecologic clinical trial descriptions for readability analysis. A total of 14% (n = 8) lacked clinical trial descriptions and linked to Clinicaltrials.gov and 7% (n = 4) only had information available through additional inquiry within the cancer center. The overall mean reading level across all NCI-CCCs was 15th-grade or collegiate-level reading. The specific readability metric analyses were as follows: FORCAST: 12.4 (range; 9.7-14.7), Fry: 17 (range; 13-17), Gunning Fog: 16.8 (range; 10-19), Raygor Estimate: 16 (range; 7-17), and SMOG: 16.5 (range; 11.4-19). Clinical trial information was stratified by the National Cancer Institute Geographic Management of Cancer Health Disparities Program, with no statistically significant differences in readability or complexity.

conclusionsIn this analysis of publicly available patient-facing information on NCI-CCC websites regarding gynecologic cancer clinical trials, the readability scores were above the high school level across the United States, which far exceeds the recommended readability metric of sixth grade by the National Institutes of Health. Opportunities exist to improve the readability of gynecologic cancer clinical trial online literature, which may facilitate patient access, participation, and understanding.

Indexed as

Clinical Trials as TopicComprehensionGenital Neoplasms, FemaleCancer Care FacilitiesCross-Sectional StudiesFemaleHumansInternetNational Cancer Institute (U.S.)United StatesClinical TrialsGynecologic OncologyHealth LiteracyReadability

Identifiers

PMID40024811
PMCPMC13577424

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.