ArticleJournal of musculoskeletal & neuronal interactions2025
Precision Errors of Lower Leg Measurement by pQCT in Children With Medical Conditions: Bone Density, Mass, Dimensions, Mechanostat Parameters and Soft Tissue Composition.
Article in Journal of musculoskeletal & neuronal interactions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Abstract
objectivesThe one of the developing methods in paediatric densitometry field is peripheral quantitative computed tomography (pQCT), however, very little is known about its precision in children. The aim of presented study was to evaluate the precision errors for bone density, mass, dimensions, strength and mechanostat parameters as well as for soft tissue composition in children with medical conditions.
methodsStratec XCT 2000L apparatus was used. The measurement sites were 4%, 14%, 38% and 66% of the lower leg length. The study group comprised of 60 patients (30 girls) aged 5,0-18,0 yrs.
resultsRelative precision errors (CV%RMS) were from 0,25% for tibia 38% cortical bone density to 5,49% for fat cross-sectional area to muscle cross-sectional area ratio. Least significant change (LSC) was from 0,70% to 15,20%, respectively. Weak to moderate correlations between precision errors and body size, with r from -0,43 to 0,71, have been observed.
conclusionPresented study revealed pQCT method at the lower leg in children with medical conditions as relatively precise technique. Obtained results provides an attainable basis for design and interpretation of pQCT studies in children with medical conditions.
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