ArticleJournal of optometry
Longitudinal change in central corneal thickness among primary schoolchildren.
Article in Journal of optometry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate the longitudinal changes in corneal thickness and its contributing factors in primary schoolchildren.
methodsThis study is a part of the Shahroud Schoolchildren Eye Cohort Study, conducted longitudinally in two phases; in 2015 and then in 2018. Participants were tested for uncorrected visual acuity, best-corrected visual acuity, cycloplegic refraction, biometry, and Scheimpflug corneal imaging.
resultsAfter applying the exclusion criteria, 8782 eyes from 4432 participants were analysed. Of these, 2309 (52.1%) were male. Average three-year changes in central corneal thickness (CCT) and corneal apex thickness were -0.58 (95% CI: -0.94 to -0.22) and -0.59 (95% CI: -0.95 to -0.23) microns, respectively. There was an increase of 8.63 (95% CI: 8.1 to 9.17) microns in the superior corneal thickness after three years while the inferior corneal thickness decreased by an average of -5.75 (95% CI: -6.3 to -5.2) microns. The multiple generalized estimating equation (GEE) model showed that the three-year changes in the CCT were lower in rural than in urban students (β = -1.71; p < 0.001). Moreover, the baseline CCT (β = -0.04; p < 0.001), anterior chamber depth (β = -1.6; p = 0.003), and corneal diameter (β = -1.18; p < 0.001) had a significant inverse association while the body mass index (β = 0.12; p = 0.002) and axial length (β = 0.84; p < 0.001) had a significant direct association with the 3-year changes in CCT. After three years, CCT decreased by advancing age in boys, while remaining almost constant in girls.
conclusionThe 3-year change in CCT was clinically negligible and could indicate its stability in schoolchildren. However, CCT thinning was more remarkable in urban students.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.