Evidence map›Paper›PMID 40023850›Full record

Observational studyAddiction (Abingdon, England)2025

Do internalising or externalising behaviours in adolescence mediate the child maltreatment-alcohol substance use relationship?

Mike Trott, Claudia Bull, Jake Moses Najman, Dan Siskind, Urska Arnautovska, Steve Kisely

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Addiction (Abingdon, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mike TrottPrincess Alexandra Hospital Southside Clinical Unit, Greater Brisbane Clinical School, Medical School, The University of Queensland, Woolloongabba, Australia.ORCID https://orcid.org/0000-0001-5978-3407
Claudia BullPrincess Alexandra Hospital Southside Clinical Unit, Greater Brisbane Clinical School, Medical School, The University of Queensland, Woolloongabba, Australia.ORCID https://orcid.org/0000-0003-4064-652X
Jake Moses NajmanSchool of Public Health, The University of Queensland, Herston, Australia.ORCID https://orcid.org/0000-0001-7079-2080
Dan SiskindPrincess Alexandra Hospital Southside Clinical Unit, Greater Brisbane Clinical School, Medical School, The University of Queensland, Woolloongabba, Australia.
Urska ArnautovskaPrincess Alexandra Hospital Southside Clinical Unit, Greater Brisbane Clinical School, Medical School, The University of Queensland, Woolloongabba, Australia.
Steve KiselyPrincess Alexandra Hospital Southside Clinical Unit, Greater Brisbane Clinical School, Medical School, The University of Queensland, Woolloongabba, Australia.ORCID https://orcid.org/0000-0003-4021-2924

Funding

Metro South Health RSS_2022_002National Health and Medical Research Council GNT1194635National Health and Medical Research Council GNT2002047Queensland Health
6 · The paper itself

Abstract

BACKGROUND AND

aimsChild maltreatment (CM) is associated with several negative mental health outcomes in later life, including alcohol and substance use (AU and SU). Internalising (e.g. anxiety and depression) and externalising (e.g. delinquency and anti-social behaviour) behaviours have also been associated with CM, and with AU and SU. This study measured whether externalising or internalising behaviours in adolescence mediate the relationship between agency-reported CM and hospital admissions for AU or SU. DESIGN, SETTING AND

participantsObservational study linking administrative health data from Queensland, Australia, to prospective birth cohort data comprising agency-reported CM up to 14 years (exposure). MEASUREMENTS: Externalising and internalising behaviours at 14 years measured using the Youth Self-Report (mediator) and administratively linked inpatient hospital admissions for AU and SU from ages 25-39 (outcome).

findingsAdjusted causal mediation analyses (n = 5092) found that externalising behaviours statistically significantly mediated 31% (P = 0.007) of the CM AU relationship, and 22% of the CM SU relationship (P = 0.016). Internalising behaviours did not statistically significantly mediate between CM and either AU or SU.

conclusionsIn Queensland, Australia, externalising behaviours appear to partially mediate the relationship between agency-reported child maltreatment and hospital admissions for alcohol and substance use, while internalising behaviours do not.

Indexed as

Adolescent BehaviorAlcohol DrinkingChild AbuseSubstance-Related DisordersAdolescentAdultChildFemaleHospitalizationHumansMaleProspective StudiesQueenslandYoung Adultadolescencealcohol use disorderchild abusechild maltreatmentexternalisingsubstance use disorder

Identifiers

PMID40023850
PMCPMC12128566

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.