Evidence map›Paper›PMID 40023800›Full record

ArticleEmerging infectious diseases2025

Mycobacterium nebraskense Isolated from Patients in Connecticut and Oregon, USA.

Mark L Metersky, Ashley J Losier, David A Fraulino, Theodore A Warnock, Cara D Varley, Angela M Le, Kevin L Winthrop, John R McArdle, Salika M Shakir, Reeti Khare

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mark L Metersky
Ashley J Losier
David A Fraulino
Theodore A Warnock
Cara D Varley
Angela M Le
Kevin L Winthrop
John R McArdle
Salika M Shakir
Reeti Khare

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Mycobacterium avium complex Core Outcomes Research (MACCOR)K23HL161495 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Cara Varley · 2022 to 2026
$850k
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS K23 HL161495
6 · The paper itself

Abstract

Mycobacterium nebraskense infection is rarely encountered; only 7 human cases have been reported worldwide since the initial report of 5 cases in Nebraska, USA, in 2004. We report 9 patients from Connecticut and 2 from Oregon, USA, who had M. nebraskense isolated from respiratory secretions; 7 patients met the American Thoracic Society/Infectious Diseases Society of America criteria for nontuberculous mycobacterial pulmonary disease. In 4 cases, the organism was isolated 1 time and caused brief or no symptoms. Most cases in Connecticut were reported after 2017. Antimicrobial drug susceptibility testing of 6 isolates showed clarithromycin susceptibility. In 2 cases, infection was refractory to treatment. The 9 Connecticut patients lived in 8 different towns; thus, a common water supply did not explain the high frequency of M. nebraskense isolation. M. nebraskense is a clinically significant cause of nontuberculous mycobacterial pulmonary disease in Connecticut; continued surveillance will be needed to determine its frequency and optimum treatment.

Indexed as

Mycobacterium Infections, NontuberculousNontuberculous MycobacteriaAdultAgedAged, 80 and overAnti-Bacterial AgentsConnecticutFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedOregonAnti-Bacterial AgentsbacteriabronchiectasisConnecticutMycobacterium nebraskensenontuberculous mycobacteriaOregonrespiratory infectionsUnited States

Identifiers

PMID40023800
PMCPMC11878316

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.