Evidence map›Paper›PMID 40023798›Full record

ArticleEmerging infectious diseases2025

Corynebacterium diphtheriae Infections, South Africa, 2015-2023.

Mignon du Plessis, Rito Mikhari, Linda de Gouveia, Noluthando Duma, Tamsin Lovelock, Charlene Lawrence, Prasha Mahabeer, Yesholata Mahabeer, Nevashan Govender, Susan Nzenze and 6 more

Abstract readHistorical Article
In one paragraph

Article in Emerging infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Mignon du Plessis
Rito Mikhari
Linda de Gouveia
Noluthando Duma
Tamsin Lovelock
Charlene Lawrence
Prasha Mahabeer
Yesholata Mahabeer
Nevashan Govender
Susan Nzenze
Jonathan Featherston
Mishalan Moodley
Jocelyn Moyes
Sibongile Walaza
Cheryl Cohen
Anne von Gottberg

Funding

Southern African-Pittsburgh Public Health Genomic Epidemiology Training Program (SAPPHGenE)D43TW011255 · FIC · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Lee H Harrison, Anne von Gottberg · 2019 to 2026
$1.7M
FIC NIH HHS D43 TW011255Wellcome Trust
6 · The paper itself

Abstract

We reviewed Corynebacterium spp. infection cases reported in South Africa during 2015-2023. We analyzed 84 isolates from 83 patients with C. diphtheriae, as well as 1 C. belfantii and 3 C. ulcerans isolates. Among C. diphtheriae cases, we observed respiratory diphtheria (26/83 patients [31%]), endocarditis (14/83 [17%]), cutaneous diphtheria (22/83 [27%]), nonspecific respiratory illnesses (5/83 [6%]), and asymptomatic carriage (16/83 [19%]). The median patient age was 19 (range 0-88) years. Diphtheria-tetanus-pertussis vaccination was incomplete for 26% (5/19) or unknown for 68% (13/19) of children 0-9 years of age. C. diphtheriae was intermediately resistant to penicillin (82/84 [98%] isolates; MIC

Indexed as

Corynebacterium diphtheriaeCorynebacterium InfectionsDiphtheriaAdolescentAdultAgedAged, 80 and overAnti-Bacterial AgentsChildChild, PreschoolCorynebacteriumFemaleHistory, 21st CenturyHumansInfantInfant, NewbornAnti-Bacterial Agents2015–2023. Emerg Infect Dis. 2025 Mar [date cited]. https://doi.org/10.3201/eid3103.241211antimicrobial resistancebacteriaCorynebacterium diphtheriaecutaneous diphtheriade Gouveia Ldiphtheriadiphtheria toxinDTP vaccineDuma Net al. Corynebacterium diphtheriae infectionsgenomeinfective endocarditisLawrence CLovelock TMikhari Rmolecular epidemiologySouth AfricaSuggested citation for this article: du Plessis Mtox gene

Identifiers

PMID40023798
PMCPMC11878320

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.