Evidence map›Paper›PMID 40022687›Full record

ArticleAsian Pacific journal of cancer prevention : APJCP2025

Liver Cancer Mortality Rates in Peru: Trend Analysis from 2003 to 2017.

J Smith Torres-Roman, Gabriel De La Cruz-Ku, Christian S Alvarez, Jorge Ybaseta-Medina, Eloy F Ruiz, Jose Fabian Martinez-Herrera, Janina Bazalar-Palacios, Lita Del Rio-Muñiz, Julio A Poterico, Katherine A McGlynn

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Article in Asian Pacific journal of cancer prevention : APJCP, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

10 authors.

J Smith Torres-RomanScientific University of the South, Lima, Peru.
Gabriel De La Cruz-KuScientific University of the South, Lima, Peru.
Christian S AlvarezDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
Jorge Ybaseta-MedinaSan Luis Gonzaga National University of Ica, Ica, Peru.ORCID 0000-0003-1224-1357
Eloy F RuizLatin American Network for Cancer Research (LAN-CANCER), Lima, Peru.
Jose Fabian Martinez-HerreraLatin American Network for Cancer Research (LAN-CANCER), Lima, Peru.
Janina Bazalar-PalaciosLatin American Network for Cancer Research (LAN-CANCER), Lima, Peru.
Lita Del Rio-MuñizLatin American Network for Cancer Research (LAN-CANCER), Lima, Peru.
Julio A PotericoFaculty of Health Sciences, Universidad de Huánuco, Huánuco 10001, Peru.ORCID 0000-0001-7838-3505
Katherine A McGlynnDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLiver cancer is one of the leading causes of cancer-related death in Peru, and some reports have indicated an increase in mortality rates among the largest cities. To our knowledge, no study has been carried out at a national level or by geographic area in recent years. Thus, our objective was to examine overall, regional and sex-specific liver cancer mortality rates in Peru between 2003-2017.

methodsWe retrieved data on liver cancer deaths between 2003 and 2017 from the mortality database of the Peruvian Ministry of Health.  Age-standardized mortality rates (ASMR) were estimated per 100,000 person-years using the world standard SEGI population. We analyzed mortality trends using Joinpoint regression Program Version 4.7.0. To examine the spatial distribution of the mortality rates, we used GeoDa software.

resultsBetween 2003 and 2017, 31,473 deaths from liver cancer were reported in Peru. Overall, liver cancer mortality rates have decreased significantly among Peruvian women since 2005 (-3.1% annually) with decreases in the coastal and highland regions ranging from 2.8% to 3.5%. In Arequipa, Cusco, La Libertad, Lima, and Moquegua, rates decreased bewteen 2003 and 2017. Among men in Ancash a significant increase (+12.5 annually) was observed from 2003-2011, followed by a sharpdecline (-10.5 annually) between  2011 and  2017.  In contrast, rates in Cajamarca, Junin, and Ucayali  decreased between  2003 and 2017.

conclusionsAlthough decreases in liver cancer mortality rates were observed in some  regions of Peru, these trends were not statistically significant. In addition, some provinces experienced  increases in rates. Effective interventions, such as expanding access to healthcare and controlling the various risk factors for liver cancer, remains a key challenge for the country.

Indexed as

Liver NeoplasmsMortalityAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPattern Analysis, MachinePeruPrognosisSurvival RateEpidemiologyGeographic spatial analysisLiver cancerMortality ratePeru

Identifiers

PMID40022687
PMCPMC12118021

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