Evidence map›Paper›PMID 40022644›Full record

ArticleThe Journal of physiology2025

α4β2

Katiuscia Martinello, Addolorata Mascia, Sara Casciato, Giancarlo Di Gennaro, Vincenzo Esposito, Michele Zoli, Cecilia Gotti, Sergio Fucile

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Katiuscia MartinelloDepartment of Human, Social & Health Sciences, University of Cassino and Southern Lazio, Cassino, Italy.ORCID 0000-0002-0423-5689
Addolorata MasciaIRCCS Neuromed, Pozzilli, Italy.
Sara CasciatoIRCCS Neuromed, Pozzilli, Italy.
Giancarlo Di GennaroIRCCS Neuromed, Pozzilli, Italy.
Vincenzo EspositoIRCCS Neuromed, Pozzilli, Italy.
Michele ZoliDepartment of Biomedical, Metabolic and Neural Sciences, Center for Neuroscience and Neurotechnology, University of Modena and Reggio Emilia, Modena, Italy.
Cecilia GottiCNR Institute of Neuroscience, Vedano al Lambro, Italy.
Sergio FucileIRCCS Neuromed, Pozzilli, Italy.ORCID 0000-0003-0698-1148

Funding

Next Generation EU- Investment 2.1 Enhancement and strengthening of biomedical research in NHS NRRP M6C2 PNRR-MAD-2022-12376434
6 · The paper itself

Abstract

Heteromeric nicotinic acetylcholine nAChRs (nAChRs) containing the α4 and β2 subunits (α4β2

Indexed as

Epilepsy, Temporal Lobegamma-Aminobutyric AcidGlutamic AcidReceptors, NicotinicTemporal LobeAdultFemaleHumansHydrocarbons, BrominatedIndole AlkaloidsInhibitory Postsynaptic PotentialsInterneuronsMaleMiddle AgedPyramidal CellsSynaptic Transmissiondesformylflustrabrominegamma-Aminobutyric AcidGlutamic AcidHydrocarbons, BrominatedIndole Alkaloidsnicotinic receptor alpha4beta2Receptors, Nicotinicdesformylflustrabromineexcitatory postsynaptic currentsinhibitory postsynaptic currentsL5 pyramidal cellspositive allosteric modulatortemporal lobe epilepsy

Identifiers

PMID40022644
PMCPMC11908476

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.