Evidence map›Paper›PMID 40022626›Full record

ArticleESC heart failure2025

Decreased endogenous nitric oxide production in acute decompensated heart failure with a reduced ejection fraction.

Roman Falls, Bing H Wang, Sara Vogrin, Christopher J Neil

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ESC heart failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Roman FallsSchool of Health and Biomedical Sciences, RMIT University, Melbourne, Australia.ORCID https://orcid.org/0000-0001-9562-194X
Bing H WangBaker Heart and Diabetes Institute, Melbourne, VIC, Australia.ORCID https://orcid.org/0000-0001-9580-2548
Sara VogrinDepartment of Medicine, University of Melbourne-Western Health, Melbourne, VIC, Australia.ORCID https://orcid.org/0000-0002-1597-9421
Christopher J NeilBaker Heart and Diabetes Institute, Melbourne, VIC, Australia.

Funding

National Health and Medical Research Council of Australia 1092642
6 · The paper itself

Abstract

aimsHeart failure represents a substantial burden to both patients and healthcare systems worldwide. Nitric oxide (NO) dysregulation may play a key role in patients transitioning from chronic to acute heart failure with a reduced ejection fraction (HFrEF). Plasma nitrite (NO METHODS AND

resultsWe utilized gas-phase chemiluminescence to determine plasma NO

conclusionsWe present novel data with regard to plasma NO

Indexed as

Heart FailureNitric OxideStroke VolumeAcute DiseaseAgedArginineBiomarkersFemaleHumansMaleMiddle AgedNitritesVascular StiffnessArginineBiomarkersNitric OxideNitritesN,N-dimethylarginineAsymmetric dimethylarginineHeart failure with a reduced ejection fractionNitric oxidePlasma nitrite

Identifiers

PMID40022626
PMCPMC12055394

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.