Evidence map›Paper›PMID 40022550›Full record

Trial reportClinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery2025

No Difference in Pain or Febrile Episodes With the Use of Post-Operative Antibiotics in Paediatric Coblation Intracapsular Tonsillectomy for Sleep-Disordered Breathing or Recurrent Tonsillitis: A Prospective Randomised Trial.

Netanel Eisenbach, Igor Yakubovich, Ahmad Bader, Ephraim Rinot, Abeer Dabbah Miari, Samah Khalil, Rania Faris, Eyal Sela, Maayan Gruber

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. [The value of tonsil ultrasound measurement in pediatric obstructive sleep apnea].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Netanel EisenbachAzrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.ORCID 0000-0003-4513-3766
Igor YakubovichAzrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Ahmad BaderAzrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Ephraim RinotAzrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Abeer Dabbah MiariDepartment of Otolaryngology-Head and Neck Surgery, Galilee Medical Center, Nahariya, Israel.
Samah KhalilDepartment of Otolaryngology-Head and Neck Surgery, Galilee Medical Center, Nahariya, Israel.
Rania FarisStatistical Analysis Division, Galilee Medical Center, Nahariya, Israel.
Eyal SelaAzrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Maayan GruberAzrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.ORCID 0000-0001-7680-1435

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCoblation technology is gaining wide acceptance and use as a contemporary surgical technique for tonsil surgeries due to less post-operative morbidity compared to the more traditional total tonsillectomy. Previous articles examined the role of post-operative antibiotics for traditional total tonsillectomy; however, this is the first study which explores the role of post-operative prophylactic antibiotic treatment among children undergoing coblation intracapsular tonsillectomy.

methodsA prospective randomised study included 100 children (aged 1-16) who were divided into two subgroups: with and without post-operative antibiotics. Post-operative follow-up of patients included assessment for 7 days of pain levels, fever, return to diet, bleeding and halitosis. In addition, the children's caregivers completed the Parents'-Postoperative-Pain-Measure (PPP-M) questionnaire on Days 1 and 7.

resultsThe (+) antibiotic subgroup had substantially less halitosis on Days 2-6 after surgery. Prophylactic antibiotic treatment did not yield any differences between the two subgroups in the incidence of fever, return to regular diet or drinking, pain as measured by the Wong Baker Faces Pain scale, or pain as reported by the parents on the PPP-M questionnaire.

conclusionsThis prospective study highlights that routine prophylactic post-operative antibiotic use has a limited clinical benefit in paediatric intracapsular tonsillectomy. Improvement in halitosis was significant with antibiotic treatment; however, various other clinical parameters did not differ between the two subgroups, so the routine use of post-operative antibiotics in the above setting is discouraged.

Indexed as

Anti-Bacterial AgentsAntibiotic ProphylaxisFeverPostoperative PainSleep Apnea SyndromesTonsillectomyTonsillitisAdolescentChildChild, PreschoolFemaleHumansInfantMalePain MeasurementProspective StudiesAnti-Bacterial Agentsantibioticcoblation‐intracapsular‐tonsillectomyfeverrecovery

Identifiers

PMID40022550
PMCPMC12128007

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.