Evidence map›Paper›PMID 40022549›Full record

ArticleClinical cardiology2025

A Potential Relationship Between HALP Score and In-Hospital Mortality in Acute Heart Failure.

Akbulut Muge, Izci Cenan, Ozyuncu Nil, K Esenboga

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Article in Clinical cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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5 citing papers in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Akbulut MugeDepartment of Cardiology, Ankara University School of Medicine, Altındağ, Turkey.ORCID http://orcid.org/0000-0002-9190-0009
Izci CenanDepartment of Cardiology, Ankara University School of Medicine, Altındağ, Turkey.
Ozyuncu NilDepartment of Cardiology, Ankara University School of Medicine, Altındağ, Turkey.
K EsenbogaDepartment of Cardiology, Ankara University School of Medicine, Altındağ, Turkey.

Funding

The authors received no specific funding for this work.
6 · The paper itself

Abstract

introductionAcute heart failure (AHF) is associated with a dismal prognosis that is even poorer than the majority of cancer types. Therefore, clinical indicators that can aid in determining the prognosis of heart failure are of interest. Multiple risk prediction tools with varying sensitivity and specificities have been introduced before. In the current study, we aimed to evaluate whether the HALP score could accurately predict in-hospital mortality in patients with AHF.

methodsWe evaluated the medical records of a total of 153 patients admitted to our institution between August 2016-May 2018 for acute heart failure. The patients were divided into two groups: Group 1 (patients who died during hospital admission) and Group 2 (patients who were discharged from the hospital). The HALP score was calculated as: hemoglobin (g/L) x albumin (g/L) x lymphocytes (/L)/platelets (/L) for each patient. The two groups were compared in terms of HALP scores. The receiver operator characteristic (ROC) curve was utilized to assess the predictive performance of HALP on in-hospital mortality in AHF.

resultsPatients who died during admission had lower HALP scores compared with the patients who were discharged uneventfully. A ROC curve analysis was performed to predict the optimal cut-off value of the HALP score. The area under the curve (AUC), sensitivity, specificity, and the cut-off value were 0.650, 43%, 57%, 21,5 respectively (p = 0.014).

conclusionDespite all evolving treatment modalities, heart failure-related mortality rates remain high. Prompt recognition of patients with an unfavorable prognosis is vital for the timely implementation of disease-modifying therapeutic interventions. The HALP score, being a readily calculable tool, serves as an effective means to pinpoint individuals at a heightened risk of in-hospital mortality. We believe that the HALP score holds promise as a practical tool for predicting in-mortality among patients admitted for AHF.

Indexed as

Heart FailureAcute DiseaseAgedAged, 80 and overFemaleHemoglobinsHospital MortalityHumansMaleMiddle AgedPredictive Value of TestsPrognosisRetrospective StudiesRisk AssessmentRisk FactorsROC CurveHemoglobinsHALP scoreheart failurein‐hospital mortality

Identifiers

PMID40022549
PMCPMC11871422

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.