Evidence map›Paper›PMID 40022541›Full record

ArticleAging cell2025

Telomeres in Space.

Abraham Aviv, Simon Verhulst

Abstract read
In one paragraph

Article in Aging cell, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Abraham AvivCenter of Human Development and Aging, New Jersey Medical School, Rutgers State University of New Jersey, Newark, New Jersey, USA.ORCID 0000-0002-7441-0227
Simon VerhulstGroningen Institute for Evolutionary Life Sciences, University of Groningen, Groningen, the Netherlands.

Funding

Elucidating the measurement of telomeres: Development of a transdisciplinary, high-impact Telomere Research NetworkU24AG066528 · NIA · TULANE UNIVERSITY OF LOUISIANA · PI DRURY, STACY SCHMIDT · 2019 to 2023
$3.0M
Impact of Phthalate Exposure on Telomere Biology in UteroR01ES035760 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ABRAHAM AVIV, Whitney Cowell · 2024 to 2026
$1.1M
Telomere Length Measurements: Strengths and LimitationsU01AG066529 · NIA · RBHS-NEW JERSEY MEDICAL SCHOOL · PI AVIV, ABRAHAM · 2019 to 2021
$911k
NIA NIH HHS U01 AG066529NIA NIH HHS U24 AG066528NIEHS NIH HHS R01 ES035760NIH HHS 1U24AG066528NIH HHS R01ES035760NIH HHS U01AG066529Research Council of Norway #262700
6 · The paper itself

Abstract

Recent studies have reported that the spaceflight environment lengthens leukocyte telomeres. We propose that this baffling finding reflects changes in the composition of leukocyte subsets rather than an actual increase in telomere length within individual leukocytes. Since leukocyte telomere length is associated with aging-related diseases and longevity in humans, it is crucial to understand the underlying factors driving telomere length changes in space.

Indexed as

Space FlightTelomereTelomere HomeostasisAgingAnimalsHumansLeukocytesastronautslymphocytesneutrophilsspacetelomeres

Identifiers

PMID40022541
PMCPMC11896355

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.