Evidence map›Paper›PMID 40022280›Full record

ArticleBrain and behavior2025

Effect of Craniocervical Atherosclerotic Stenosis on the Occurrence of Neurologic Deterioration in Patients With Small Vessel Occlusion Stroke and Their Clinical Outcomes.

Wei Han, Yue He, YuanWei Shao, Pacifique Sibomana, Yi Yang, Ming Yu

Abstract read
In one paragraph

Article in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wei HanDepartment of Neurology, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu, China.ORCID https://orcid.org/0009-0000-0429-266X
Yue HeDepartment of Neurology, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu, China.
YuanWei ShaoDepartment of Radiology, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu, China.
Pacifique SibomanaKibagabaga Level II Teaching Hospital, Kigali, Rwanda.
Yi YangDepartment of Neurology, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu, China.
Ming YuDepartment of Neurology, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the effects of craniocervical atherosclerotic stenosis (AS) on the occurrence of neurologic deterioration (ND) in patients with small vessel occlusion (SVO) stroke and the outcomes of patients with SVO stroke with ND (SVO-ND).

methodsPatients with SVO stroke were consecutively enrolled. AS was defined as a craniocervical artery with ≥ 50% stenosis caused by atherosclerosis.

resultsThe presence of craniocervical AS (adjusted odds ratio [aOR] = 2.57, 95% confidence interval [CI] = 1.12-5.89, p = 0.026) and the number of craniocervical AS (aOR = 2.08, 95% CI = 1.25-3.44, p = 0.005) were associated with the occurrence of ND in patients with SVO stroke. Compared with SVO stroke patients with no craniocervical AS, the risk of ND increased in those with multiple AS (aOR = 6.47, 95% CI = 1.73-24.05, p = 0.005). The risk of poor outcomes increased in SVO-ND patients with multiple AS than SVO-ND patients with no AS (aOR = 47.75, 95% CI = 1.66-375.17, p = 0.024).

conclusionThe presence and the number of craniocervical AS are associated with ND in SVO stroke patients and with poststroke disability in SVO-ND patients.

Indexed as

AtherosclerosisIntracranial ArteriosclerosisIschemic StrokeStrokeAgedAged, 80 and overConstriction, PathologicFemaleHumansMaleMiddle Agedclinical outcomecraniocervical atherosclerotic stenosisneurologic deteriorationsmall vessel occlusion stroke

Identifiers

PMID40022280
PMCPMC11870831

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.