Evidence map›Paper›PMID 40022247›Full record

Trial reportJournal of health, population, and nutrition2025

Effect of perioperative individualized nutrition intervention on pancreatic surgery outcomes: a prospective single-center study.

Qing Chen, Chunhong Xiao, Xusangni Li, Qian Li, Huishuang Wu, Meiping Wang, Weixuan Hong, Aiwen Huang

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of health, population, and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qing ChenFuzong Clinical Medical College of Fujian Medical University, Fuzhou, Fujian Province, 350025, China.
Chunhong XiaoDepartment of General Surgery, 900th Hospital of Joint Logistic Support Force, Fuzhou, Fujian Province, 350025, China.
Xusangni LiDepartment of Nutrition, 900th Hospital of Joint Logistic Support Force, Fuzhou, Fujian Province, 350025, China.
Qian LiDepartment of Nutrition, 900th Hospital of Joint Logistic Support Force, Fuzhou, Fujian Province, 350025, China.
Huishuang WuDepartment of Anesthesiology, 900th Hospital of Joint Logistic Support Force, Fuzhou, Fujian Province, 350025, China.
Meiping WangDepartment of General Surgery, 900th Hospital of Joint Logistic Support Force, Fuzhou, Fujian Province, 350025, China.
Weixuan HongDepartment of General Surgery, 900th Hospital of Joint Logistic Support Force, Fuzhou, Fujian Province, 350025, China.
Aiwen HuangDepartment of Clinical Pharmacy, 900th Hospital of Joint Logistic Support Force, Fuzhou, Fujian Province, 350025, China. hawen83@sina.com.

Funding

Fujian Medical University 2020QH1251
6 · The paper itself

Abstract

backgroundThere is currently a lack of reports on prospective randomized controlled trials (RCTs) focused on personalized nutritional support in pancreatic surgery. This study aimed to evaluate the impact of perioperative individualized nutritional intervention on the outcomes of patients undergoing pancreatic surgery within the framework of enhanced recovery after surgery (ERAS).

methodsThis prospective cohort study enrolled 96 patients, randomly divided into a trial group and a control group in a 1:1 ratio. The primary endpoint was the change in body composition, including body cell mass (BCM), fat-free mass (FFM), skeletal muscle mass (SMM), and phase angle (PA). Secondary outcomes included time to first postoperative flatus, time to first bowel movement, length of hospital stay, and nutritional indicators.

resultsNo significant differences were observed in the demographic characteristics between the two groups. The ratio of actual total calorie intake to recommended daily intake in the trial group was significantly higher than the control group (87.01% vs. 69.50%, P < 0.001). The ratio of actual protein intake to recommended daily intake was significantly higher in the trial group than the control group (96.18% vs.76.29%, P < 0.001). In body composition data, significant differences were found between the two groups in the ratio of BCM, FFM, and SMM at the study endpoint compared to admission. Additionally, a significant difference between the two groups was present in the ratio of BCM, FFM, and SMM at the third postoperative day (POD 3) compared with those at admission. While no significant differences were found between the groups in time to first flatus and time to first stool, the trial group had a significantly shorter postoperative hospital stay compared to the control group (15.9d vs. 20.4d, P = 0.046). Nutritional index analysis revealed a statistically significant difference in the ratio of serum total protein at the study endpoint compared POD 3 (P < 0.05), but no significant differences were found in serum prealbumin, albumin, and hemoglobin.

conclusionsPersonalized nutritional interventions throughout the perioperative period improved patients' nutritional status and reduced the length of postoperative hospital stay.

Indexed as

Nutritional SupportPancreasPerioperative CarePrecision MedicineAgedBody CompositionEnergy IntakeEnhanced Recovery After SurgeryFemaleHumansLength of StayMaleMiddle AgedNutritional StatusProspective StudiesTreatment OutcomeIndividualized nutritionNutrition supportPancreatic surgeryPhase angle

Identifiers

PMID40022247
PMCPMC11871664

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.