Evidence map›Paper›PMID 40022224›Full record

ArticleJournal of health, population, and nutrition2025

Analysis of non-tuberculous mycobacteria types in high tuberculosis endemic areas.

Na-Na Li, Lu-Lu Gao, Mei Liu, Wan-Min Zhang, Xiao-Ke Zhang, Ling Chen, Zhaojing Zong, Yuanbo Lan

Abstract read
In one paragraph

Article in Journal of health, population, and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Diagnostic performance of MALDI-TOF MS for non-tuberculous mycobacteria: A systematic review and meta-analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Na-Na LiDepartment of Tuberculosis, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, 563003, China. 252578718@qq.com.
Lu-Lu GaoDepartment of Tuberculosis, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, 563003, China.
Mei LiuDepartment of Tuberculosis, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, 563003, China.
Wan-Min ZhangDepartment of Tuberculosis, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, 563003, China.
Xiao-Ke ZhangDepartment of Tuberculosis, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, 563003, China.
Ling ChenDepartment of Tuberculosis, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, 563003, China. lingjuncd@163.com.
Zhaojing ZongDepartment of Tuberculosis, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, 563003, China.
Yuanbo LanDepartment of Tuberculosis, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, 563003, China. lee15085116731@sina.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of non-tuberculous mycobacteria (NTM) has been rising globally, posing significant challenges for diagnosis and treatment, particularly in regions with high tuberculosis (TB) incidence. This study aims to investigate the epidemiological, demographic, and clinical characteristics of non-tuberculous mycobacterial lung disease (NTM-PD) in areas with a high incidence of TB.

methodThis study was conducted at the Affiliated Hospital of Zunyi Medical University from January 2017 to December 2021. A total of 6259 culture-positive specimens were analyzed. Screening was based on acid-fast staining, colony morphology, and p-nitrobenzoic acid detection, which identified 107 suspected NTM strains. Gene sequencing confirmed 51 NTM-positive cases.

resultsThe predominant species identified were Mycobacterium abscessus (33.33%) and Mycobacterium intracellulare (27.45%). Several risk factors were associated with higher susceptibility to NTM-PD suspect, including bronchiectasis, low serum albumin levels (< 3.5 g/L), and male gender. The study found that although the isolation rate of NTM remained stable over the five-year period, drug resistance rates for the dominant species were notably high.

conclusionsThe findings highlight the need for clinicians in TB-endemic areas to carefully distinguish NTM infections from TB. The stable isolation rates of NTM, coupled with the high drug resistance of key species, underscore the importance of accurate diagnosis and tailored treatment strategies to manage NTM-PD effectively.

Indexed as

Endemic DiseasesMycobacterium Infections, NontuberculousNontuberculous MycobacteriaTuberculosisAdultAgedChinaFemaleHumansIncidenceMaleMiddle AgedRisk FactorsYoung Adult

Identifiers

PMID40022224
PMCPMC11871818

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.