Evidence map›Paper›PMID 40022134›Full record

ArticleJournal of neuroinflammation2025

Myelin-reactive CD8

Mohit Upadhye, Connor R Wilhelm, Kai J Rogers, Chakrapani Vemulawada, Nicholas Borcherding, Alexander W Boyden, Kevin L Legge, Nitin J Karandikar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neuroinflammation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Research progress on the mechanism of FOXO protein in sepsis.Apoptosis : an international journal on programmed cell death · 2026
    Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mohit UpadhyeDepartment of Pathology, University of Iowa Health Care, 200 Hawkins Drive, C660 GH, Iowa City, IA, 52242, USA.
Connor R WilhelmDepartment of Pathology, University of Iowa Health Care, 200 Hawkins Drive, C660 GH, Iowa City, IA, 52242, USA.
Kai J RogersDepartment of Pathology, University of Iowa Health Care, 200 Hawkins Drive, C660 GH, Iowa City, IA, 52242, USA.
Chakrapani VemulawadaDepartment of Pathology, University of Iowa Health Care, 200 Hawkins Drive, C660 GH, Iowa City, IA, 52242, USA.
Nicholas BorcherdingDepartment of Pathology and Immunology, Washington University in St. Louis, 660 S. Euclid Ave, St. Louis, MO, 63110, USA.
Alexander W BoydenDepartment of Pathology, University of Iowa Health Care, 200 Hawkins Drive, C660 GH, Iowa City, IA, 52242, USA.
Kevin L LeggeDepartment of Pathology, University of Iowa Health Care, 200 Hawkins Drive, C660 GH, Iowa City, IA, 52242, USA.
Nitin J KarandikarDepartment of Pathology, University of Iowa Health Care, 200 Hawkins Drive, C660 GH, Iowa City, IA, 52242, USA. nitin-karandikar@uiowa.edu.ORCID http://orcid.org/0000-0002-6867-6950

Funding

BLRD VA I01 BX003677CSRD VA I01 CX002319U.S. Department of Veterans Affairs I01BX003677
6 · The paper itself

Abstract

Multiple sclerosis (MS), an autoimmune demyelinating disease of the central nervous system, is modeled in mice as experimental autoimmune encephalomyelitis (EAE). While CD4

Indexed as

CD8-Positive T-LymphocytesDendritic CellsEncephalomyelitis, Autoimmune, ExperimentalMyelin SheathAdoptive TransferAnimalsCell DifferentiationCells, CulturedFemaleMiceMice, Inbred C57BLMice, TransgenicMyelin Proteolipid ProteinPhenotypeMyelin Proteolipid Protein

Identifiers

PMID40022134
PMCPMC11869544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.