ArticleBMC cancer2025
Two or three weeks of thyroid hormone withdrawal before initial
Article in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Pediatric papillary thyroid carcinoma: postoperative management and 14-year experience with radioiodine therapy at a Portuguese oncology centre.European journal of pediatrics · 2026Observational
- Unexpected Cancellation of Radioactive Iodine Treatment after Thyroid Hormone Withdrawal: Lessons from a Case Series.Endocrinology and metabolism (Seoul, Korea) · 2026Article
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3 authors.
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Abstract
objectiveTo evaluate the effects of different thyroid hormone withdrawal (THW) duration before initial
methodsDTC patients who underwent total thyroidectomy between January 2016 and August 2018 before initial
resultsTotally, 95.3% (303/318) of patients had TSH ≥ 30 mIU/L after THW. The rate of TSH ≥ 30 mIU/L in groups A and B was 93.8% (152/162) and 96.8% (151/156), respectively (P = 0.212). Age was the only factor influencing TSH ≥ 30 mIU/L (hazard ratio [HR] 0.937, 95% confidence interval [CI] 0.882-0.997, P = 0.038). Changes of creatinine, alanine aminotransferase, aspartate aminotransferase, cholesterol, high-density lipoprotein and low-density lipoprotein before and after THW were higher in group B than in group A (all P < 0.05). After a median follow-up of 55 months, the rate of disease persistence/recurrence in groups A and B was 6.2% (7/113) and 2.3% (3/128), respectively (P = 0.241). Stimulated thyroglobulin before
conclusionsTwo-week THW was an effective strategy to achieve TSH ≥ 30 mIU/L before
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