ArticleBMC public health2025
Association between the triglyceride glucose-body mass index and mortality risk in cardiovascular disease populations: a longitudinal cohort study.
Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Risk Factors for Cardiovascular Disease: Epidemiology, Screening, Prevention, and Therapeutic Interventions.MedComm · 2026Review
- Association between triglyceride glucose-body mass index and all-cause mortality in critically ill patients with atherosclerotic cardiovascular diseases: a retrospective cohort study using the MIMIC-IV database.BMC cardiovascular disorders · 2026Article
- Development and Validation of a Machine Learning-Based Prediction Model for Cardiovascular Disease in Patients with Metabolic Dysfunction-Associated Fatty Liver Disease.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2026Article
- Association between triglyceride glucose-body mass index and incident risk of heart failure among patients with type 2 diabetes: a real-world study.Frontiers in endocrinology · 2026Observational
- Review on the Relationship Between TyG Index and CVD Incidence in Patients With T2DM With NAFLD.International journal of endocrinology · 2026Review
- Higher Dietary Insulinemic Potential, and Triglyceride-Glucose (TyG)-BMI Index may Contribute to Coronary Artery Disease Severity: a Cross-Sectional Study.Journal of epidemiology and global health · 2025Article
- Association between C-reactive protein-triglyceride glucose index and all-cause mortality and premature death: a joint analysis based on case data from the Central Hospital of Shaoyang and CHARLS database.Frontiers in medicine · 2025Article
- Insulin resistance markers HOMA-IR, TyG and TyG-BMI index in relation to heart failure risk: NHANES 2011-2016.PloS one · 2025Article
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11 authors.
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Abstract
backgroundCardiovascular disease (CVD) is a leading cause of global mortality, with increasing prevalence and impact, especially in the elderly and developing countries. Insulin resistance (IR) plays a significant role in CVD progression, and the triglyceride glucose-body mass index (TyG-BMI) index, combining fasting glucose and triglycerides, offers a simple, cost-effective method for assessing IR. However, its prognostic value in CVD populations remains underexplored. This study aims to investigate the relationship between TyG-BMI and mortality in CVD patients.
methodsData from the National Health and Nutrition Examination Survey (NHANES) (1999-2018) combined with the linked National Death Index were analyzed. The CVD population was split into two groups (Q1 and Q2) based on the median TyG-BMI. The primary outcomes were all-cause mortality and cause-specific mortality.
resultsThe study ultimately included 2,576 participants, of which 56% were male. The median age of the participants was 69 years, and the median TyG-BMI was 256.59. After adjusting for potential confounders, a negative relationship was found between TyG-BMI and all-cause mortality in populations with CVD, coronary heart disease (CHD), congestive heart failure (CHF), and heart attack. The hazard ratios (HR) and 95% confidence intervals (CI) were 0.73 (0.64, 0.85), 0.67 (0.53, 0.84), 0.69 (0.54, 0.88), and 0.73 (0.59, 0.91), respectively. At the same time, a notable inverse relationship was noted between the TyG-BMI and non-CVD mortality in the CVD and CHD population, with HR and 95% CI of 0.70 (0.58, 0.84) and 0.61 (0.45, 0.82), respectively. In this study, there was no observed noteworthy relationship between TyG-BMI and CVD mortality. Furthermore, sensitivity analysis yielded similar results.
conclusionAmong populations with CVD in the United States, a heightened TyG-BMI was notably correlated with a decreased likelihood of mortality. This index can effectively classify the risk levels of CVD patients and may serve as a valuable prognostic marker.
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