Evidence map›Paper›PMID 40021908›Full record

ArticleBrain and behavior2025

Post-Thrombectomy Mild Hypercapnia State Prevents Poor Outcome by Reducing Infarct Progression.

Peng Jiang, Weitao Yu, Xu Wang, Shouxuan Gao, Yu Geng, Shunyuan Guo, Qiang Shen, Longting Lin, Mark Parsons, Sheng Zhang

Abstract read
In one paragraph

Article in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Peng JiangCenter for Rehabilitation Medicine, Department of Neurology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, China.ORCID https://orcid.org/0009-0007-8219-2665
Weitao YuThe Second School of Clinical Medicine, Hangzhou Normal University, Hangzhou, China.
Xu WangCenter for Rehabilitation Medicine, Department of Neurology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, China.
Shouxuan GaoCenter for Rehabilitation Medicine, Department of Neurology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, China.
Yu GengCenter for Rehabilitation Medicine, Department of Neurology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, China.
Shunyuan GuoCenter for Rehabilitation Medicine, Department of Neurology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, China.ORCID https://orcid.org/0009-0004-1226-0683
Qiang ShenCenter for Rehabilitation Medicine, Department of Radiology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, China.
Longting LinSchool of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia.
Mark ParsonsDepartment of Neurology, Liverpool Hospital, University of New South Wales, Sydney, New South Wales, Australia.
Sheng ZhangCenter for Rehabilitation Medicine, Department of Neurology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, China.

Funding

the Medical Health Science and Technology Project of the Zhejiang Provincial Health Commission 2022KY600the Medical Health Science and Technology Project of the Zhejiang Provincial Health Commission 2024KY019the Medical Health Science and Technology Project of the Zhejiang Provincial Health Commission 2024KY756Zhejiang Provincial Natural Science Foundation of China LGF22H090020
6 · The paper itself

Abstract

objectiveIn endovascular therapy (EVT) for stroke, futile recanalization contributes to poor prognosis. Mild hypercapnia may enhance cerebral blood flow and prevent ischemia, but its impact on prognosis in successfully recanalized EVT patients is unclear.

methodsWe retrospectively analyzed 237 patients from the INSPIRE database who underwent successful recanalization at our center (October 2018-March 2022). Patients were grouped by post-EVT PaCO

resultsHigh PaCO

conclusionMaintaining mild hypercapnia (PaCO

Indexed as

HypercapniaStrokeThrombectomyAgedCerebrovascular CirculationDisease ProgressionEndovascular ProceduresFemaleHumansMaleMiddle AgedPrognosisRetrospective StudiesTreatment Outcomeendovascular therapyfutile recanalizationinfarct progressmild hypercapniastroke prognosis

Identifiers

PMID40021908
PMCPMC11870790

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.