Evidence map›Paper›PMID 40021840›Full record

ReviewJournal of perinatology : official journal of the California Perinatal Association2026

Pulmonary function tests in the neonatal intensive care unit and beyond: a clinical review.

Mitzi A Go, Kelvin D MacDonald, Manuel Durand, Cindy T McEvoy

Abstract readReview
In one paragraph

Review in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mitzi A GoDivision of Neonatology, Department of Pediatrics, Oregon Health & Science University, Portland, OR, USA.ORCID http://orcid.org/0000-0001-7098-3223
Kelvin D MacDonaldDivision of Pediatric Pulmonology, Department of Pediatrics, Oregon Health & Science University, Portland, OR, USA.ORCID http://orcid.org/0000-0002-6716-8559
Manuel DurandDivision of Neonatology, Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-1131-5783
Cindy T McEvoyDivision of Neonatology, Department of Pediatrics, Oregon Health & Science University, Portland, OR, USA. mcevoyc@ohsu.edu.ORCID http://orcid.org/0000-0001-8501-8813

Funding

Oregon Clinical and Translational Research Institute KL2 SupplementKL2TR002370 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Catherine Lee Hough · 2017 to 2026
$10.1M
VitC to Decrease Effects of Smoking in Pregnancy on Infant Lung Function-CCC-LeadR01HL105447 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI MCEVOY, CYNTHIA T · 2012 to 2021
$9.8M
Extending CPAP Therapy in Stable Preterm Infants to Increase Lung Growth and Function: A Randomized Controlled TrialR33HL147906 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI MCEVOY, CYNTHIA T, TEPPER, ROBERT S. · 2020 to 2023
$2.7M
NCATS NIH HHS KL2 TR002370NHLBI NIH HHS R01 HL105447NHLBI NIH HHS R33 HL147906Oregon Health & Science University | Oregon Clinical and Translational Research Institute (Oregon Clinical & Translational Research Institute) KL2TR002370U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL105447U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) R33HL147906U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) RO1HL105447
6 · The paper itself

Abstract

Pulmonary function tests (PFTs) in the Neonatal Intensive Care Unit (NICU) have played a pivotal role in neonatal care. They have helped quantify the effects of therapeutic interventions, guide ventilator management, and serve as endpoints in clinical trials. Preterm delivery, the most common cause of altered lung development, establishes early lung function trajectories that persist into later life. Early PFTs in preterm infants can enhance our understanding of factors influencing these trajectories. This review summarizes techniques performed in the NICU and early infancy and the evolution of continuous lung function monitoring through the bedside ventilator. It provides examples incorporating PFTs in the NICU and early infancy to improve outcomes and identifies evolving technology in this area. This review does not include studies of control of breathing in newborn infants. Looking ahead, the field would greatly benefit from developing a sustainable, non-invasive PFT technique that can be applied across the lifespan.

Indexed as

Intensive Care Units, NeonatalLungRespiratory Function TestsHumansInfant, NewbornInfant, PrematureRespiration, Artificial

Identifiers

PMID40021840
PMCPMC13123290

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.