Evidence map›Paper›PMID 40021776›Full record

ArticleScientific reports2025

Assessment of antibacterial, nematicidal and herbicidal activities of Cautleya spicata (Sm.) Baker extracts, with chemical profiling using GC-MS.

Sonu Kumar Mahawer, Himani Karakoti, Ravendra Kumar, Om Prakash, Satya Kumar, Shilpi Rawat, Dharmendra Singh Rawat, Pushpendra Koli, Shivangi Chamoli, Piyush Kumar and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sonu Kumar MahawerDepartment of Chemistry, College of Basic Sciences and Humanities, G.B. Pant University of Agriculture and Technology, U.S. Nagar, Pantnagar, Uttarakhand, India.
Himani KarakotiDepartment of Chemistry, College of Basic Sciences and Humanities, G.B. Pant University of Agriculture and Technology, U.S. Nagar, Pantnagar, Uttarakhand, India.
Ravendra KumarDepartment of Chemistry, College of Basic Sciences and Humanities, G.B. Pant University of Agriculture and Technology, U.S. Nagar, Pantnagar, Uttarakhand, India. ravichemistry.kumar@gmail.com.
Om PrakashDepartment of Chemistry, College of Basic Sciences and Humanities, G.B. Pant University of Agriculture and Technology, U.S. Nagar, Pantnagar, Uttarakhand, India.
Satya KumarDepartment of Plant Pathology, College of Agriculture, G.B. Pant University of Agriculture and Technology, U.S. Nagar, Pantnagar, Uttarakhand, India.
Shilpi RawatDepartment of Plant Pathology, College of Agriculture, G.B. Pant University of Agriculture and Technology, U.S. Nagar, Pantnagar, Uttarakhand, India.
Dharmendra Singh RawatDepartment of Biological Sciences, College of Basic Science and Humanities, G.B. Pant, University of Agriculture and Technology, U.S. Nagar, Pantnagar, Uttarakhand, India.
Pushpendra KoliICAR-Indian Grassland and Fodder Research Institute, Jhansi, Uttar Pradesh, India.
Shivangi ChamoliDepartment of Biotechnology, Graphic Era Deemed to be University, Dehradun, Uttarakhand, India.
Piyush KumarSchool of Health Sciences and Technology, University of Petroleum and Energy Studies, Bidholi, Dehradun, Uttarakhand, India.
Jolanta MaslowieckaInstitute of Forest Sciences, Bialystok Technology University, Bialystok, Poland.
Valery A IsidorovInstitute of Forest Sciences, Bialystok Technology University, Bialystok, Poland.
Yonglin RenMurdoch University, Perth, Australia. Y.Ren@murdoch.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pesticidal activity of the rhizome and aerial parts of Cautleya spicata (Sm.) Baker was investigated, revealing significant findings. The GC-MS analysis revealed significant compositional variability among the extracts. β-Sitosterol was identified as the dominant compound in all extracts prepared with hexane, acetone, and methanol, while α-humulene was prominently present in the rhizome extracts. The methanolic extracts of C. spicata demonstrated substantial nematicidal activity against Meloidogyne incognita and herbicidal activity against seeds of Raphanus raphanistrum subsp. Sativus (L.) (Radish) and Cichorium intybus L. (Chicory). Additionally, the extracts exhibited effective antibacterial activities against four bacterial strains, including Salmonella enterica serotype typhi, Escherichia coli, Listeria monocytogenes, and Staphylococcus aureus. In-silico molecular docking studies identified stigmasterol as exhibiting the best binding affinities with the studied proteins. These results highlight the potential of C. spicata extracts as promising candidates for the development of botanical pesticides and antibacterial agents.

Indexed as

Anti-Bacterial AgentsAntinematodal AgentsPlant ExtractsAnimalsGas Chromatography-Mass SpectrometryMicrobial Sensitivity TestsMolecular Docking SimulationRhizomeTylenchoideaAnti-Bacterial AgentsAntinematodal AgentsPlant ExtractsAntibacterialCautleya spicataGC-MSHerbicidal activityNematicidal activityPlant extract

Identifiers

PMID40021776
PMCPMC11871356

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.