Evidence map›Paper›PMID 40021764›Full record

ArticleNPJ digital medicine2025

Transfer learning method for prenatal ultrasound diagnosis of biliary atresia.

Fujiao He, Gang Li, Zhichao Zhang, Chaoran Yang, Zeyu Yang, Hao Ding, Dan Zhao, Wei Sun, Yu Wang, Kaihui Zeng and 11 more

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Fujiao He *Department of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.ORCID http://orcid.org/0000-0002-9358-9656
Gang Li *Department of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Zhichao ZhangCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang, Liaoning, China.
Chaoran YangCentral Laboratory, The Second Affiliated Hospital of the Chinese University of Hong Kong, Shenzhen, Guangdong, China.
Zeyu YangDepartment of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Hao DingDepartment of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Dan ZhaoDepartment of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Wei SunDepartment of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Yu WangDepartment of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Kaihui ZengDepartment of Obstetrics, First People's Hospital of Yunnan Province, Kunming, Yunnan, China.
Xian LiDepartment of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Mingming ShaoDepartment of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Jiao YinDepartment of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Jia YaoDepartment of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Boxuan HongDepartment of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Zhibo ZhangDepartment of Pediatric Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Zhengwei YuanKey Laboratory of Health Ministry for Congenital Malformation, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Zongjie WengDepartment of Medical Ultrasonics, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian, China. wengzongjie1984@fjmu.edu.cn.
Luyao ZhouDepartment of Ultrasound, Shenzhen Children's Hospital, Shenzhen, Guangdong, China. zhouly6@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0002-1828-0878
Mo ZhangDepartment of Urology, The First Hospital of China Medical University, Shenyang, Liaoning, China. peterzhang623@gmail.com.
Lizhu ChenDepartment of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China. aliceclz@sina.com.

Funding

National Natural Science Foundation of China (National Science Foundation of China) No.82170529National Natural Science Foundation of China (National Science Foundation of China) No.82173372National Natural Science Foundation of China (National Science Foundation of China) No.82272022
6 · The paper itself

Abstract

Biliary atresia (BA) is a rare and severe congenital disorder with a significant challenge for prenatal diagnosis. This study, registered at the Chinese Clinical Trial Registry (ChiCTR2200059705), aimed to develop an intelligent model to aid in the prenatal diagnosis of BA. To develop and evaluate this model, fetuses from 20 hospitals across China and infants sourced from public database were collected. The transfer-learning model (TLM) demonstrated superior diagnostic performance compared to the basic deep-learning model, with higher area under the curves of 0.906 (95%CI: 0.872-0.940) vs 0.793 (0.743-0.843), 0.914 (0.875-0.953) vs 0.790 (0.727-0.853), and 0.907 (0.869-0.945) vs 0.880 (0.838-0.922) for the three independent test cohorts. Furthermore, when aided by the TLM, diagnostic accuracy surpassed that of individual sonologists alone. The TLM achieved satisfactory performance in predicting fetal BA, providing a low-cost, easily accessible, and accurate diagnostic tool for this condition, making it an effective aid in clinical practice.

Identifiers

PMID40021764
PMCPMC11871324

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.