Evidence map›Paper›PMID 40021720›Full record

ArticleCommunications biology2025

Resveratrol does not mimic the positive effects of calorie restriction on lifespan in Microcebus murinus.

Fabien Pifferi, Jérémy Terrien, Julia Marchal, Alexandre Dal-Pan, Fathia Djelti, Martine Perret, Jacques Epelbaum, Stéphane Blanc, Jean-Luc Picq, Marc Dhenain and 1 more

Abstract read
In one paragraph

Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Aging and cancer: current understandings and future perspectives.Signal transduction and targeted therapy · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Fabien PifferiUMR CNRS MNHN 7179, Mécanismes Adaptatifs et Evolution, Brunoy, France. fabien.pifferi@mnhn.fr.ORCID http://orcid.org/0000-0001-9316-1935
Jérémy TerrienUMR CNRS MNHN 7179, Mécanismes Adaptatifs et Evolution, Brunoy, France.ORCID http://orcid.org/0000-0001-8530-4481
Julia MarchalUMR CNRS MNHN 7179, Mécanismes Adaptatifs et Evolution, Brunoy, France.
Alexandre Dal-PanUMR CNRS MNHN 7179, Mécanismes Adaptatifs et Evolution, Brunoy, France.
Fathia DjeltiUMR CNRS MNHN 7179, Mécanismes Adaptatifs et Evolution, Brunoy, France.ORCID http://orcid.org/0000-0002-0163-3198
Martine PerretUMR CNRS MNHN 7179, Mécanismes Adaptatifs et Evolution, Brunoy, France.
Jacques EpelbaumUMR CNRS MNHN 7179, Mécanismes Adaptatifs et Evolution, Brunoy, France.
Stéphane BlancUniversité de Strasbourg, CNRS, IPHC UMR 7178, Strasbourg, France.
Jean-Luc PicqDysCo Laboratory, Paris 8 Saint-Denis University, Paris, France.
Marc DhenainUniversité Paris-Saclay, CEA, CNRS, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.
Fabienne AujardUMR CNRS MNHN 7179, Mécanismes Adaptatifs et Evolution, Brunoy, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resveratrol (RSV), a polyphenol with anti-aging properties affecting metabolism and energy balance, is considered as a mimetic candidate to calorie restriction (CR). However its potential effects on delaying the onset of age-related diseases and increasing longevity have not yet been demonstrated in non-obese models close to humans such as non-human primates. The longitudinal monitoring of cognitive and motor performances, occurrence of age-related pathologies, age-related brain atrophy and mortality was performed from adulthood to death in a cohort of male grey mouse lemurs (Microcebus murinus, N = 33), all receiving 105 kJ/day of food but with a subset of 18 animals receiving RSV (200 mg.kg

Indexed as

Caloric RestrictionCheirogaleidaeLongevityResveratrolAgingAnimalsCognitionMaleResveratrol

Identifiers

PMID40021720
PMCPMC11871233

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.