ArticleScientific reports2025
Bidirectional association between ADL disability and depressive symptoms among older adults: longitudinal evidence from CHARLS.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Effects of an early restrictive versus liberal fluid strategy on long-term patient-centered outcomes in sepsis-induced hypotension: an open-label, randomized controlled trial.American journal of respiratory and critical care medicine · 2026Trial
- Machine Learning Classification of Current Functional Impairment in Older Adults with Diabetes: Evidence from CHARLS 2015.Journal of clinical medicine · 2026Article
- Multidimensional determinants of depression and non-depression in older adults: evidence from national data.BMC geriatrics · 2026Article
- Joint Association of Functional Impairment and Depression with Advanced Cardiovascular-Kidney-Metabolic Syndrome: A Cross-Sectional and Cohort Study Using Two Large Datasets.Healthcare (Basel, Switzerland) · 2026Article
- Clowning in care: long-term effectiveness of clown visits on residents' affect, resilience, sleep quality and functionality.BMC geriatrics · 2026Article
- Long-term care insurance pilot exposure and severe-depression risk among older adults with baseline severe IADL impairment: a panel difference-in-difference-in-differences analysis.BMC geriatrics · 2026Article
- Caregivers' burden and psychiatric morbidity among informal caregivers of older adults: results from a national survey.BMC geriatrics · 2026Article
- Network-based identification of central ADL and IADL items in older adults living alone.BMC geriatrics · 2026Article
- Associations of metals and micronutrients with functional disability in Chinese older adults: a mixture analysis approach.Scientific reports · 2026Article
- Physical disorders, ADLs, cognition, and depression in nursing home residents: a parallel mediation analysis.BMC geriatrics · 2026Article
- The association between nighttime sleep duration and digestive diseases in middle-aged and older population in China: mediating role of depression.BMC public health · 2026Article
- Complex associations of adverse childhood and adulthood experiences with incident depressive symptoms in middle-aged and older Chinese adults.BMC psychology · 2026Article
- Development of a Practical Nomogram for Depression Risk Stratification in Older Adults With Hypertension and Diabetes: Retrospective Analysis of Data From the China Health and Retirement Longitudinal Study.JMIR medical informatics · 2026Article
- High-Frequency Functional Trajectories Predict Depressive Worsening in Singapore's Community-Dwelling Older Adults.Healthcare (Basel, Switzerland) · 2026Article
- The association between internet use and cognition in older adults: empirical analysis based on CLASS 2023.Frontiers in psychology · 2026Article
- Association of vitamin D deficiency with incident depression in patients with hearing impairment: an observational retrospective cohort study.Frontiers in nutrition · 2026Article
- Depressive trajectories and their associations with chronic diseases among older adults: a national longitudinal cohort study from China.BMC geriatrics · 2025Article
- The Mediating Role of Activities of Daily Living in the Relationship Between Depressive Symptoms and Multidimensional Frailty in the Elderly with Multimorbidity.Clinical interventions in aging · 2025Article
- Identification of optimal cutoffs for obesity and lipid-related indices in screening activities of daily living disability in Chinese middle-aged and elderly adults.Frontiers in nutrition · 2025Article
- Digital inclusion and depressive symptoms among Chinese older adults: The moderating role of cognitive function.Digital healthArticle
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Authors and funding
6 authors.
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Abstract
This study investigates the bidirectional relationship between Activities of Daily Living (ADL) disability and depressive symptoms (DS) among middle-aged and older adults in China, utilizing data from the China Health and Retirement Longitudinal Study (CHARLS) from 2015 to 2018. A total of 8994 participants were analyzed to assess the impact of ADL on the risk of depressive symptoms, while 9673 participants were included to examine the influence of depressive symptoms on the risk of ADL disability. Cox proportional hazards regression models were employed to evaluate these relationships, adjusting for sociodemographic, lifestyle, and health-related covariates. Results revealed that ADL disability significantly increased the risk of depressive symptoms (HR = 1.090, 95% CI 1.058-1.123), and depressive symptoms were associated with a higher risk of ADL disability (HR = 1.033, 95% CI 1.025-1.042). Subgroup analyses demonstrated that factors such as education level, social activity, and disability significantly modified the relationship between ADL and depressive symptoms, while age, marital status, and pain influenced the association between depressive symptoms and ADL. Sensitivity analyses confirmed the robustness of these findings. This study highlights the complex interplay between ADL and depressive symptoms, emphasizing the need for targeted interventions to mitigate the risk of depression and improve functional independence in aging populations.
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