Evidence map›Paper›PMID 40021618›Full record

ArticleNature communications2025

CatPred: a comprehensive framework for deep learning in vitro enzyme kinetic parameters.

Veda Sheersh Boorla, Costas D Maranas

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Article
  2. Predicting Enzyme Turnover Numbers and Enabling Rational Enzyme Evolution.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. High-throughput physics-based enzyme engineering.bioRxiv : the preprint server for biology · 2026
    Article
  4. Review
  5. Review
  6. Article
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  8. Article
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  11. Review
  12. On why cancer cells require a great amount of glucose.Quantitative biology (Beijing, China) · 2026
    Article
  13. Article
  14. Article
  15. Review
  16. Article
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  18. Article
  19. Enzyme Catalytic Parameters and Evolution Across the Dissipation Plane.International journal of molecular sciences · 2026
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Veda Sheersh BoorlaDepartment of Chemical Engineering, The Pennsylvania State University, University Park, PA, 16802, USA.ORCID http://orcid.org/0000-0003-0084-3975
Costas D MaranasDepartment of Chemical Engineering, The Pennsylvania State University, University Park, PA, 16802, USA. cdm8@psu.edu.ORCID http://orcid.org/0000-0002-1508-1398

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Estimation of enzymatic activities still heavily relies on experimental assays, which can be cost and time-intensive. We present CatPred, a deep learning framework for predicting in vitro enzyme kinetic parameters, including turnover numbers (k

Indexed as

Deep LearningEnzymesKineticsUncertaintyEnzymes

Identifiers

PMID40021618
PMCPMC11871309

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.