Evidence map›Paper›PMID 40021614›Full record

ArticleInternational journal of oral science2025

Expert consensus on the prevention and treatment of enamel demineralization in orthodontic treatment.

Lunguo Xia, Chenchen Zhou, Peng Mei, Zuolin Jin, Hong He, Lin Wang, Yuxing Bai, Lili Chen, Weiran Li, Jun Wang and 22 more

Abstract readConsensus Statement
In one paragraph

Article in International journal of oral science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Lunguo Xia *Department of Orthodontics, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, College of Stomatology, Shanghai Jiao Tong University, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China.
Chenchen Zhou *State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Pediatric Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu, China.ORCID 0000-0002-6427-5869
Peng Mei *Department of Orthodontics, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, College of Stomatology, Shanghai Jiao Tong University, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China.
Zuolin JinState Key Laboratory of Military Stomatology, National Clinical Research Center for Oral Diseases, Shaanxi Clinical Research Center for Oral Diseases, Department of Orthodontics, School of Stomatology, Air Force Medical University, Xi'an, China.
Hong HeDepartment of Orthodontics, Hubei-MOST KLOS and KLOBM, School & Hospital of Stomatology, Wuhan University, Wuhan, China.ORCID 0000-0002-9234-0015
Lin WangDepartment of Orthodontics, Affiliated Stomatological Hospital of Nanjing Medical University, Jiangsu Province Key Laboratory of Oral Diseases, Nanjing, China.
Yuxing BaiDepartment of Orthodontics, Capital Medical University School of Stomatology, Beijing, China.
Lili ChenDepartment of Stomatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, School of Stomatology, Tongji Medical College, Huazhong University of Science and Technology, Hubei Province Key Laboratory of Oral and Maxillofacial Development and Regeneration, Wuhan, China.ORCID 0000-0002-9965-8990
Weiran LiDepartment of Orthodontics, Peking University School and Hospital of Stomatology, National Center of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing Key Laboratory of Digital Stomatology, Beijing, China.
Jun WangState Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Min HuDepartment of Orthodontics, Hospital of Stomatology, Jilin University, Changchun, China.
Jinlin SongDepartment of Orthodontics, Stomatological Hospital of Chongqing Medical University, Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China.
Yang CaoDepartment of Orthodontics, Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, China.
Yuehua LiuDepartment of Orthodontics, Shanghai Stomatological Hospital, Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China.ORCID 0000-0003-3033-8873
Benxiang HouCenter for Microscope Enhanced Dentistry, Capital Medical University School of Stomatology, Beijing, China.
Xi WeiDepartment of Operative Dentistry and Endodontics, Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, China.ORCID 0000-0002-5749-2910
Lina NiuDepartment of Prosthodontics, School of Stomatology, Air Force Medical University, State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Key Laboratory of Stomatology, Xi'an, China.ORCID 0000-0002-6653-0819
Haixia LuDepartment of Preventive Dentistry, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, College of Stomatology, Shanghai Jiao Tong University, National Center of Stomatology, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China.
Wensheng MaTianjin Stomatological Hospital, School of Medicine, Nankai University, Tianjin Key Laboratory of Oral and Maxillofacial Function Reconstruction, Tianjin, China.
Peijun WangDepartment of Orthodontics, School of Stomatology, Harbin Medical University, the Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Guirong ZhangDepartment of Orthodontics, Shenyang Stomatological Hospital, Shenyang, China.
Jie GuoDepartment of Orthodontics, School and Hospital of Stomatology, Shandong University, Jinan, China.
Zhihua LiDepartment of Orthodontics, Affiliated Stomatological Hospital of Nanchang University, Jiangxi Provincial Key Laboratory of Oral Biomedicine, Nanchang, China.
Haiyan LuDepartment of Orthodontics, School and Hospital of Stomatology, Hebei Medical University, Hebei Provincial Key Laboratory of Stomatology, Hebei Provincial Clinical Research Center for Oral Diseases, Shijiazhuang, China.
Liling RenSchool of Stomatology, Lanzhou University, Lanzhou, China.
Linyu XuDepartment of Orthodontics, Fujian Key Laboratory of Oral Diseases, Stomatological Key Lab of Fujian College and University, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China.
Xiuping WuDepartment of Orthodontics, School and Hospital of Stomatology, Shanxi Medical University, Shanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Taiyuan, China.
Yanqin LuDepartment of Orthodontics, Xiangya Stomatology Hospital, Central South University, Changsha, China.
Jiangtian HuDepartment of Orthodontics, Affiliated Stomatological Hospital of Kunming Medical University, Kunming, China.
Lin YueDepartment of Cariology and Endodontology, Peking University School and Hospital of Stomatology, National Center for Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing Key Laboratory of Digital Stomatology, Beijing, China. kqlinyue@bjmu.edu.cn.
Xu ZhangSchool and Hospital of Stomatology, Institute of Stomatology, Tianjin Medical University, Tianjin Key Laboratory of Oral Soft and Hard Tissues Restoration and Regeneration, Tianjin, China. zhangxu@tmu.edu.cn.
Bing FangDepartment of Orthodontics, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, College of Stomatology, Shanghai Jiao Tong University, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China. fangbing@sjtu.edu.cn.

Funding

National Natural Science Foundation of China (National Science Foundation of China) 11932012National Natural Science Foundation of China (National Science Foundation of China) 32171348
6 · The paper itself

Abstract

Enamel demineralization, the formation of white spot lesions, is a common issue in clinical orthodontic treatment. The appearance of white spot lesions not only affects the texture and health of dental hard tissues but also impacts the health and aesthetics of teeth after orthodontic treatment. The prevention, diagnosis, and treatment of white spot lesions that occur throughout the orthodontic treatment process involve multiple dental specialties. This expert consensus will focus on providing guiding opinions on the management and prevention of white spot lesions during orthodontic treatment, advocating for proactive prevention, early detection, timely treatment, scientific follow-up, and multidisciplinary management of white spot lesions throughout the orthodontic process, thereby maintaining the dental health of patients during orthodontic treatment.

Indexed as

Dental CariesDental EnamelTooth DemineralizationHumansTooth Remineralization

Identifiers

PMID40021614
PMCPMC11871012

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.