Evidence map›Paper›PMID 40021564›Full record

ArticleInternational urology and nephrology2025

Impact of obesity on in-hospital outcomes in peritoneal dialysis patients: insights from a nationwide analysis.

Wisit Kaewput, Charat Thongprayoon, Supawadee Suppadungsuk, Supawit Tangpanithandee, Wannasit Wathanavasin, Fawad Qureshi, Wisit Cheungpasitporn

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Article in International urology and nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wisit KaewputDepartment of Military and Community Medicine, Phramongkutklao College of Medicine, Bangkok, 10400, Thailand.
Charat ThongprayoonDivision of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN, 55905, USA. charat.thongprayoon@gmail.com.
Supawadee SuppadungsukDivision of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN, 55905, USA.
Supawit TangpanithandeeDivision of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN, 55905, USA.
Wannasit WathanavasinDivision of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN, 55905, USA.
Fawad QureshiDivision of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN, 55905, USA.
Wisit CheungpasitpornDivision of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN, 55905, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity is a growing public health concern and may influence outcomes in end-stage kidney disease (ESKD) patients undergoing peritoneal dialysis (PD). However, its impact on in-hospital complications, mortality, and healthcare utilization in this population remains unclear. This study aimed to assess the association between obesity and hospitalization-related outcomes in PD patients.

methodsThis study was conducted using the National Inpatient Sample to identify hospitalized ESKD patients receiving PD from the year 2003 to 2018. The in-hospital treatments, outcomes, and resource utilization were compared between obese and non-obese patients, adjusting for age, sex, race, year of hospitalization, and comorbidities.

resultsA total of 100,523 hospitalized ESKD patients receiving PD were included in the analysis. Of these, 9890 (9.8%) had obesity diagnosis. In the adjusted analysis, obese patients had a higher need for procedures for PD catheter adjustment or removal (OR 1.29; 95% CI 1.16-1.43), hemodialysis (OR 1.28; 95% CI 1.19-1.38), and mechanical ventilation (OR 1.29; 95% CI 1.16-1.44), compared to non-obese patients. Obesity was significantly associated with higher risk of PD peritonitis (OR 1.12; 95% CI 1.06-1.19) and fluid overload (OR 1.34; 95% CI 1.23-1.45) but lower in-hospital mortality (OR 0.84; 95% CI 0.73-0.96). There was no significant difference in length of hospital stay and hospitalization cost between obese and non-obese patients.

conclusionAmong hospitalized PD patients, obesity is associated with higher PD-related complications and increased need for interventions but is paradoxically linked to lower in-hospital mortality. These findings provide new insights into the obesity paradox in PD and highlight the need for tailored management strategies to mitigate obesity-related risks in hospitalized PD patients.

Indexed as

Kidney Failure, ChronicObesityPeritoneal DialysisAdultAgedFemaleHospitalizationHospital MortalityHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeUnited StatesHospitalizationMortalityObesityPD-related complicationsPeritoneal dialysisResource utilization

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.