Evidence map›Paper›PMID 40021528›Full record

ReviewOrthopadie (Heidelberg, Germany)2025

[Bone marrow edema and osteonecrosis in sport : Relevance, prognosis and therapy].

Matthias Brockmeyer, Henning Madry, Patrick Orth

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Orthopadie (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Matthias BrockmeyerKlinik für Orthopädie und Orthopädische Chirurgie, Universitätsklinikum des Saarlandes, Kirrberger Straße, Gebäude 37-38, 66421, Homburg/Saar, Deutschland. matthias.brockmeyer@uks.eu.
Henning MadryKlinik für Orthopädie und Orthopädische Chirurgie, Universitätsklinikum des Saarlandes, Kirrberger Straße, Gebäude 37-38, 66421, Homburg/Saar, Deutschland.
Patrick OrthUniversitätsklinik für Allgemeine Orthopädie, Auguste-Viktoria-Klinik, Ruhr-Universität Bochum, Bad Oeynhausen, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSports activities lead to loading stress for the osteochondral unit of the joints, especially for the lower extremity. Athletes frequently suffer from articular cartilage defects, meniscus and ligament injuries, which are often associated with subchondral bone marrow edema and osteonecrosis.

objectivesPresentation of relevance, prognosis and therapeutic options for bone marrow edema and osteonecrosis in sport. MATERIAL AND

methodsThis review describes the clinical relevance, prognostic aspects and potential treatment options for bone marrow edema and osteonecrosis in athletes.

resultsSubchondral bone marrow edema and osteonecrosis frequently occur in athletes. Most commonly, they are caused by mechanical joint overload due to sporting activities, but they are also found posttraumatically and postoperatively. Their clinical relevance to athletes remains unclear. A stepwise treatment concept includes non-surgical as well as surgical treatment options for symptomatic bone marrow edema and osteonecrosis in sport with different clinical prognoses depending on severity and location of the lesion.

conclusionsBone marrow edema and osteonecrosis may have a relevant impact on the joint function in athletes. They play a decisive role in the rehabilitation following joint injuries and surgeries and are associated with the clinical outcomes following joint injuries and have critical influence on the return to sporting activities. LEVEL OF EVIDENCE: IV, narrative review.

Indexed as

Athletic InjuriesBone Marrow DiseasesEdemaOsteonecrosisHumansPrognosisAthletesBone marrow diseaseCartilage, articularJoint diseasesLower extremity

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.