Evidence map›Paper›PMID 40021484›Full record

ArticleInorganic chemistry2025

Discovery of Phototoxic Metal Complexes with Antibacterial Properties via a Combinatorial Approach.

Timothy Kench, Nasima Sultana Chowdhury, Khondaker Miraz Rahman, Ramon Vilar

Abstract read
In one paragraph

Article in Inorganic chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Halogenated Vitamin BACS omega · 2026
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Timothy KenchDepartment of Chemistry, Imperial College London, White City Campus, 82 Wood Lane, London W12 OBZ, U.K.
Nasima Sultana ChowdhuryInstitute of Pharmaceutical Science, King's College London, Franklin-Wilkins Building, 150 Stamford Street, London SE1 9NH, U.K.
Khondaker Miraz RahmanInstitute of Pharmaceutical Science, King's College London, Franklin-Wilkins Building, 150 Stamford Street, London SE1 9NH, U.K.ORCID 0000-0001-8566-8648
Ramon VilarDepartment of Chemistry, Imperial College London, White City Campus, 82 Wood Lane, London W12 OBZ, U.K.ORCID 0000-0003-2992-199X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance is one of the biggest global healthcare challenges. Therefore, there is an urgent need to develop new molecules that display distinct antibacterial properties to overcome resistance. With this aim, we have developed a combinatorial and semiautomated platform to synthesize and screen a library of 78 compounds against Gram-positive and Gram-negative bacteria. This library is based on octahedral iridium(III) complexes with general formula [Ir(

Indexed as

Anti-Bacterial AgentsCombinatorial Chemistry TechniquesCoordination ComplexesDrug DiscoveryIridiumPhotosensitizing AgentsEscherichia coliGram-Positive BacteriaLightMicrobial Sensitivity TestsMolecular StructureStaphylococcus aureusStructure-Activity RelationshipAnti-Bacterial AgentsCoordination ComplexesIridiumPhotosensitizing Agents

Identifiers

PMID40021484
PMCPMC11920948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.