Evidence map›Paper›PMID 40021308›Full record

ArticleThe Lancet. Global health2025

Associations between the Bolsa Familia conditional cash transfer programme and substance use disorder hospitalisations: a quasi-experimental study of the 100 Million Brazilian Cohort.

Lidiane Toledo, Erika Fialho, Flávia Alves, Maurício L Barreto, Vikram Patel, Daiane B Machado

Abstract read
In one paragraph

Article in The Lancet. Global health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Lidiane ToledoCenter of Data and Knowledge Integration for Health, Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Parque Tecnológico da Bahia, Salvador, Bahia, Brazil. Electronic address: epilidi.toledo@gmail.com.
Erika FialhoCenter of Data and Knowledge Integration for Health, Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Parque Tecnológico da Bahia, Salvador, Bahia, Brazil.
Flávia AlvesCenter of Data and Knowledge Integration for Health, Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Parque Tecnológico da Bahia, Salvador, Bahia, Brazil; Department of Global Health and Social Medicine, Harvard Medical School, Boston, MA, USA.
Maurício L BarretoCenter of Data and Knowledge Integration for Health, Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Parque Tecnológico da Bahia, Salvador, Bahia, Brazil.
Vikram PatelDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, MA, USA.
Daiane B MachadoCenter of Data and Knowledge Integration for Health, Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Parque Tecnológico da Bahia, Salvador, Bahia, Brazil; Department of Global Health and Social Medicine, Harvard Medical School, Boston, MA, USA.

Funding

The impact of social drivers, conditional cash transfers and their mechanisms on mental health of the young: an integrated retrospective and forecasting approach using the 100 million Brazilian CohortR01MH128911 · NIMH · FUNDACAO OSWALDO CRUZ · PI Daiane Borges Machado · 2022 to 2026
$1.9M
NIMH NIH HHS R01 MH128911
6 · The paper itself

Abstract

backgroundAlthough low socioeconomic status is a recognised risk factor for substance use disorders (SUDs), the potential of socioeconomic interventions, such as conditional cash transfer programmes, to mitigate this burden remains poorly explored. Our study investigated whether the Brazilian conditional cash transfer, the Bolsa Familia Program (BFP) was associated with reduced SUD hospitalisations (ie, both admission to and treatment within hospital).

methodsThis quasi-experimental study used national administrative hospitalisation and BFP payroll records linked to the 100 Million Brazilian Cohort baseline from 2008 to 2015. We used Poisson regression models with inverse probability of treatment weighting, using the propensity score, to evaluate the association of the BFP with SUD hospitalisations.

findingsThe study included 35 926 326 individuals registered at baseline from 2008 to 2015. BFP benefit was associated with a lower risk of SUD hospitalisations overall (incidence rate ratios [IRR] 0·83, 95% CI 0·81-0·85). BFP benefit was also associated with both a lower risk of alcohol-related hospitalisations (0·74, 0·71-0·77) and a lower risk of hospitalisations due to other substances except alcohol (0·89, 0·86-0·92). Both male and female beneficiaries had a lower risk of SUD hospitalisation compared with non-beneficiaries. We observed an increased gradient of protection against SUD hospitalisations among beneficiaries of the BFP as municipal deprivation increased. The reduction was 10% (IRR 0·90, 0·87-0·92) in less deprived municipalities and 41% (0·59, 0·49-0·71) in highly deprived municipalities.

interpretationReceiving BFP benefit was associated with lower risk of SUD hospitalisation, implicating conditional cash transfers as a potential tool to respond to SUD-related issues in individuals experiencing poverty. This protective association could be mediated by alleviating poverty, fulfilling basic needs, improving socioeconomic status, enhancing health access, and promoting education.

fundingNational Institute of Mental Health-National Institutes of Health. TRANSLATION: For the Portuguese translation of the abstract see Supplementary Materials section.

Indexed as

HospitalizationSubstance-Related DisordersAdolescentAdultBrazilCohort StudiesFemaleHumansMaleMiddle AgedSocioeconomic FactorsYoung Adult

Identifiers

PMID40021308
PMCPMC11916922

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.