Evidence map›Paper›PMID 40021273›Full record

ArticleJACC. Advances2025

Diagnostic Accuracy Prior to Congenital Heart Defect Surgery: A Multicenter Collaboration.

Shobha S Natarajan, Kasey Chaszczewski, Chris Penney, Steve Ampah, Douglas Ryba, Andrea T Kennedy, Robert Olsen, Shubhika Srivastava, Matthew J Campbell, Mya Carney and 31 more

Abstract read
In one paragraph

Article in JACC. Advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

41 authors.

Shobha S NatarajanDivision of Cardiology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA. Electronic address: natarajans@chop.edu.
Kasey ChaszczewskiDivision of Cardiology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA; Division of Cardiology, Children's Wisconsin, Milwaukee, Wisconsin, USA.
Chris PenneyDivision of Cardiology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Steve AmpahDivision of Cardiology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Douglas RybaDivision of Cardiology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Andrea T KennedyDivision of Cardiology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Robert OlsenDivision of Cardiology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Shubhika SrivastavaDivision of Cardiology, Nemours Children's Health, Wilmington, Delaware, USA.
Matthew J CampbellDivision of Cardiology, Nemours Children's Health, Wilmington, Delaware, USA.
Mya CarneyDivision of Cardiology, Nemours Children's Health, Wilmington, Delaware, USA.
Carol ProsperoDivision of Cardiology, Nemours Children's Health, Wilmington, Delaware, USA.
Lisa ElliottDivision of Cardiology, Nemours Children's Health, Wilmington, Delaware, USA.
Carlie BrewerDivision of Cardiology, Children's Hospital Denver, Denver, Colorado, USA.
Michael DiMariaDivision of Cardiology, Children's Hospital Denver, Denver, Colorado, USA.
Nitin MadanDivision of Cardiology, Children's Mercy Hospital, Kansas City, Missouri, USA.
Seda TierneyDivision of Cardiology, Lucile Packard Children's Hospital, Stanford, California, USA.
Meaghan BeattieDivision of Cardiology, Lucile Packard Children's Hospital, Stanford, California, USA.
Ritu SachdevaDivision of Pediatric Cardiology, Emory University and Children's Healthcare of Atlanta, Atlanta, Georgia, USA.
Joan LipinskiChildren's Healthcare of Atlanta, Atlanta, Georgia, USA.
Kenan W D SternDivision of Cardiology, Mount Sinai Kravis Children's Hospital, New York, New York, USA.
Grace KongDivision of Cardiology, Mount Sinai Kravis Children's Hospital, New York, New York, USA.
Preeta DhanantwariDivision of Pediatric Cardiology, Long Island Jewish Medical Center at Northwell Health, New Hyde Park, New York, USA.
Elena N KwonDivision of Pediatric Cardiology, Long Island Jewish Medical Center at Northwell Health, New Hyde Park, New York, USA.
Hari RajagopalDivision of Pediatric Cardiology, Long Island Jewish Medical Center at Northwell Health, New Hyde Park, New York, USA.
Carolyn TaylorDivision of Pediatric Cardiology, The Medical University of South Carolina, Charleston, South Carolina, USA.
Tammy ChurchillDivision of Pediatric Cardiology, The Medical University of South Carolina, Charleston, South Carolina, USA.
Aura A Sanchez MejiaDivision of Cardiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.
Deidra Abenlah AnsahDivision of Cardiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.
Anitha ParthibanDivision of Cardiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.
Hasti SanandajifarDivision of Cardiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.
Sowmya BalasubramanianDivision of Cardiology, C.S. Mott Children's Hospital, Ann Arbor, Michigan, USA.
David A ParraDivision of Cardiology, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, Tennessee, USA.
Kimberly CrumDivision of Cardiology, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, Tennessee, USA.
Corey StiverDivision of Cardiology, Nationwide Children's Hospital, Columbus, Ohio, USA.
Aarti H BhatDivision of Cardiology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA.
Pei-Ni JoneDivision of Cardiology, Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.
Stefani SamplesDivision of Cardiology, Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.
Kathleen Van't HofDivision of Cardiology, Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.
Curt DeGroffDivision of Pediatric Cardiology, University of Florida, Gainsville, Florida, USA.
Dalia Lopez-ColonDivision of Pediatric Cardiology, University of Florida, Gainsville, Florida, USA.
Meryl S CohenDivision of Cardiology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEchocardiography is the mainstay for diagnosing congenital heart disease (CHD). Diagnostic errors can lead to suboptimal surgical outcomes.

objectivesThis multicenter pediatric echocardiography collaborative learning initiative explores reasons for diagnostic errors, investigates associations between patient- and center-specific factors and errors, and relays the benefits of a multicenter approach to decrease these errors as a first step to improve CHD surgical outcomes.

methodsParticipating centers submitted diagnostic evaluations on patients prior to 2-ventricle repair into a central database. We held virtual meetings to revise variables and discuss cases to learn from each other.

resultsFourteen pediatric echocardiography laboratories entered data on 1,476 consecutive patients with specific cardiac diagnoses who underwent a two-ventricle repair over 11 months. The mean error rate across centers was 7.1% (103 errors, 17/126-6/125). Seventy-six (74%) errors were preventable or possibly preventable. Cognitive (43%) and imaging factors (47%) commonly contributed to these errors. Moderate to severe impact on postoperative outcomes occurred in 19 (25%) preventable or possibly preventable errors. There were no statistically significant associations between patient- or center-specific factors and errors.

conclusionsThis work represents the feasibility and advantages of a multicenter approach to preoperative diagnostic errors. Variability existed in sedated protocols, number of echos needed, use of other modalities, and in other processes. Common anatomic areas were found. Rather than undertaking isolated, single-center projects, this collaborative is poised to learn about novel changes that would improve diagnostic accuracy across centers as a first step to advancing surgical outcomes for patients with CHD.

Indexed as

echocardiography (echo) laboratory (lab)pediatric diagnostic errorsquality improvement (QI)

Identifiers

PMID40021273
PMCPMC11905157

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.