Evidence map›Paper›PMID 40021204›Full record

Trial reportRMD open2025

EducAR: implementing a multicomponent strategy to improve therapeutic adherence in rheumatoid arthritis.

María Ahijón Lana, Francisca Sivera Mascaró, Antonio Fernández-Nebro, Sara Muntadas Castelló, Marina Pérez, Teresa Otón, María Jesús García de Yébenes, Loreto Carmona, EDUCAR Group

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in RMD open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05425485 (educAR), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05425485 nacompletednot on this map

educAR: Validation of a Double Educational Strategy to Improve Therapeutic Adherence in Rheumatoid Arthritis.

TypeinterventionalSponsorMaría AhijónRan2022 to 2023Enrolled142ConditionsRheumatoid ArthritisArmsMulti-component intervention
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

María Ahijón LanaHospital Universitario de la Princesa, Madrid, Spain maria.ahijon@salud.madrid.org.
Francisca Sivera MascaróRheumatology Department, Universidad Miguel Hernandez de Elche - Facultad de Medicina, Sant Joan d'Alacant, Spain.
Antonio Fernández-NebroHospital Regional Universitario de Málaga, Málaga, Spain.ORCID 0000-0002-2962-9844
Sara Muntadas CastellóLliga Reumatològica Catalana, Barcelona, Spain.
Marina PérezPontia Design, Berlin, Germany.
Teresa OtónInstituto de Salud Musculoesquelética SL, Madrid, Spain.
María Jesús García de YébenesInstituto de Salud Musculoesquelética SL, Madrid, Spain.
Loreto CarmonaInstituto de Salud Musculoesquelética SL, Madrid, Spain.ORCID 0000-0002-4401-2551
EDUCAR Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe EULAR points to consider (PtC) for reducing non-adherence need implementation.

objectivesTo design, implement and evaluate a strategy based on the PtC to improve treatment adherence in rheumatoid arthritis (RA).

methodsA multidisciplinary panel cocreated an intervention that was subsequently tested in a cluster trial, where centres were randomised to access the developed intervention or follow the standard of care (SOC). 6-month initiation and implementation adherence were measured in consecutive patients with <2 years of RA. The results were discussed among the centres assigned to the intervention to explore barriers and facilitators to implementation.

resultsThe intervention was a two-sided website. The items on the patient site mainly addressed disease and treatment education, self-management and peer support. The healthcare professional site has tutorials on communication to improve trust and adherence, plus shared decision-making aids. It was tested in 141 RA patients (67 control and 74 intervention). Both groups increased adherence at 6 months, mainly in the control group (48% to 67% vs 42% to 47% in the intervention group). Implementation had been very low in relation to barriers identified as lack of time, inadequate focus (exclusively for nurses) and consideration of the current SOC as adequate.

conclusionDespite designing an intervention based on the best evidence, the results were inconclusive; the lack of a detected effect could be explained by the limited implementation, which was insufficient for the complexity of the changes required (change of culture). TRIAL REGISTER NUMBER: ClinicalTrials.gov ID NCT05425485.

Indexed as

Antirheumatic AgentsArthritis, RheumatoidMedication AdherencePatient Education as TopicAgedFemaleHumansMaleMiddle AgedSelf-ManagementAntirheumatic AgentsOutcome and Process Assessment, Health CarePatient Care TeamQualitative research

Identifiers

PMID40021204
PMCPMC11873333

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.