Evidence map›Paper›PMID 40020687›Full record

ReviewCell genomics2025

National investment case development for pathogen genomics.

Yoong Khean Khoo, Suci Wulandari, Marya Getchell, La Moe, Shurendar Selva Kumar, Elyssa Jiawen Liu, Yimei Sun, Junxiong Pang, Swapnil Mishra, Hannah Clapham and 5 more

Abstract readReview
In one paragraph

Review in Cell genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yoong Khean KhooCentre for Outbreak Preparedness, Duke-NUS Medical School, Singapore, Singapore; SingHealth Duke-NUS Global Health Institute, Duke-NUS Medical School, Singapore, Singapore; Centre of Regulatory Excellence, Duke-NUS Medical School, Singapore, Singapore. Electronic address: khooyk@duke-nus.edu.sg.
Suci WulandariCentre for Outbreak Preparedness, Duke-NUS Medical School, Singapore, Singapore; SingHealth Duke-NUS Global Health Institute, Duke-NUS Medical School, Singapore, Singapore.
Marya GetchellProgram in Health Services and Systems Research, Duke-NUS Medical School, Singapore, Singapore.
La MoeCentre for Outbreak Preparedness, Duke-NUS Medical School, Singapore, Singapore; Emerging Infectious Diseases Program, Duke-NUS Medical School, Singapore, Singapore.
Shurendar Selva KumarCentre for Outbreak Preparedness, Duke-NUS Medical School, Singapore, Singapore.
Elyssa Jiawen LiuCentre for Outbreak Preparedness, Duke-NUS Medical School, Singapore, Singapore.
Yimei SunCentre for Outbreak Preparedness, Duke-NUS Medical School, Singapore, Singapore.
Junxiong PangCentre for Outbreak Preparedness, Duke-NUS Medical School, Singapore, Singapore; SingHealth Duke-NUS Global Health Institute, Duke-NUS Medical School, Singapore, Singapore.
Swapnil MishraSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Hannah ClaphamSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Ben MaraisSydney Infectious Diseases Institute, The University of Sydney, Camperdown, NSW, Australia.
Vitali SintchenkoSydney Infectious Diseases Institute, The University of Sydney, Camperdown, NSW, Australia; Centre for Infectious Diseases and Microbiology - Public Health, Westmead Hospital, Westmead, NSW, Australia; Centre for Infectious Diseases and Microbiology Laboratory Services, NSW Health Pathology - Institute of Clinical Pathology and Medical Research, Westmead, NSW, Australia.
Ruklanthi de AlwisCentre for Outbreak Preparedness, Duke-NUS Medical School, Singapore, Singapore; SingHealth Duke-NUS Global Health Institute, Duke-NUS Medical School, Singapore, Singapore; Emerging Infectious Diseases Program, Duke-NUS Medical School, Singapore, Singapore.
David HipgraveCentre for Outbreak Preparedness, Duke-NUS Medical School, Singapore, Singapore; SingHealth Duke-NUS Global Health Institute, Duke-NUS Medical School, Singapore, Singapore; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Paul Michael PronykCentre for Outbreak Preparedness, Duke-NUS Medical School, Singapore, Singapore; SingHealth Duke-NUS Global Health Institute, Duke-NUS Medical School, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sustaining and expanding genomic surveillance capacity requires broader investment in genomics that target both novel and pandemic pathogens. Currently, there is no standardized methodology to evaluate the cost and benefit of a multi-pathogen surveillance system. We propose a framework for pathogen genomic surveillance that links public health and systems considerations to a stepwise approach.

Indexed as

GenomicsInvestmentsHumansPandemicsPublic Healthdisease surveillancegenomicsglobal healthinvestment casenext-generation sequencingpandemic preparednesspathogen genomicssurveillance

Identifiers

PMID40020687
PMCPMC11960516

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.