Evidence map›Paper›PMID 40020633›Full record

ArticleEnvironment international2025

Individual effects and interactions between ultrafine particles and extreme temperatures on hospital admissions of high burden diseases.

Quan Qi, Yukang Xue, Najm Alsadat Madani, Randy T Tangang, Fangqun Yu, Arshad Nair, Xiaobo Xue Romeiko, Gan Luo, Isa Brackett, Chris Thorncroft and 1 more

Abstract read
In one paragraph

Article in Environment international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Quan QiDepartment of Economics, University at Albany, State University of New York, Albany, NY 12222, USA.
Yukang XueDepartment of Educational Psychology, University at Albany, State University of New York, Rensselaer, NY 12144, USA.
Najm Alsadat MadaniInstitute for Health and the Environment, University at Albany, State University of New York, Rensselaer, NY 12144, USA.
Randy T TangangDepartment of Environmental Health Science, School of Public Health, University at Albany, State University of New York, Rensselaer, NY 12144, USA.
Fangqun YuAtmosphere Science Research Center, University at Albany, State University of New York, Albany, NY 12222, USA.
Arshad NairAtmosphere Science Research Center, University at Albany, State University of New York, Albany, NY 12222, USA.
Xiaobo Xue RomeikoDepartment of Environmental Health Science, School of Public Health, University at Albany, State University of New York, Rensselaer, NY 12144, USA.
Gan LuoAtmosphere Science Research Center, University at Albany, State University of New York, Albany, NY 12222, USA.
Isa BrackettDepartment of Environmental Health Science, School of Public Health, University at Albany, State University of New York, Rensselaer, NY 12144, USA.
Chris ThorncroftAtmosphere Science Research Center, University at Albany, State University of New York, Albany, NY 12222, USA.
Shao LinDepartment of Environmental Health Science, School of Public Health, University at Albany, State University of New York, Rensselaer, NY 12144, USA; Department of Epidemiology and Biostatistics, School of Public Health, University at Albany, State University of New York, Rensselaer, NY 12144, USA. Electronic address: slin@albany.edu.

Funding

Weather extremes, natural disasters, and health outcomes among vulnerable older adults: New improvements on exposure assessment, disparity identification, and risk communication strategiesR01AG070949 · NIA · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI LIN, SHAO · 2022 to 2025
$1.6M
NIA NIH HHS R01 AG070949
6 · The paper itself

Abstract

backgroundHealth effects of ultrafine particles (UFPs) and their interactions with temperature are less studied. We investigated the risks of UFPs concentrations and extreme temperatures on hospitalizations for high-burden diseases (HBDs) in New York State (NYS).

methodsThis case-crossover study included hospitalizations for HBDs that contain ischemic heart diseases, diabetes, stroke, kidney diseases, and depression using NYS Hospital Discharge Data (2013-2018). Daily pollutants and temperature data were obtained from a chemical transport model validated by multiple prior studies. UFP changes were measured using interquartile range increase, and extreme heat and cold were defined as temperatures >= 90th% and <=10th% respectively by month and location. Conditional logistic regression was applied controlling for criteria pollutants, relative humidity, and time-varying variables.

resultsAmong 1,308,518 cases, significant risk ratios (RR) were observed for UFPs (RRs ranged: 1.009-1.012) and extreme heat (RRs ranged: 1.024-1.028) on overall HBDs, but extreme cold had protective effects on HBDs. The adverse effect of UFPs had significant interactions with extreme cold and was higher in winter and fall. UFPs affected all HBD subtypes except kidney diseases, and extreme heat increased the risks of ischemic heart disease and kidney disease. There were disparities across demographics in exposures-HBDs associations although they were not statistically significant. Elevated UFP concentrations were associated with four clinical indicators (hospital stays, charges etc.).

conclusionWe observe positive associations between elevated UFP concentrations or extreme heat and HBD hospitalizations, but negative associations with extreme cold. The UFPs' risks were higher in children and during cold seasons.

Indexed as

Air PollutantsAir PollutionEnvironmental ExposureExtreme HeatHospitalizationParticulate MatterAdultAgedCross-Over StudiesFemaleHumansMaleMiddle AgedNew YorkAir PollutantsParticulate MatterClinical indicatorsExtreme temperatureHigh burden diseasesHospital admissionSociodemographic disparityUltrafine particle concentration

Identifiers

PMID40020633
PMCPMC12212358

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.