Evidence map›Paper›PMID 40020192›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

A degenerate telomerase RNA directs telomeric DNA synthesis in lepidopteran insects.

Yu-Shu Chou, Dhenugen Logeswaran, Chi-Nga Chow, Phoebe L Dunn, Joshua D Podlevsky, Tianxiang Liu, Khadiza Akhter, Julian J-L Chen

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. A degenerate telomerase RNA directs telomeric DNA synthesis in lepidopteran insects.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yu-Shu ChouSchool of Molecular Sciences, Arizona State University, Tempe, AZ 85281.ORCID 0009-0009-8285-6809
Dhenugen LogeswaranSchool of Molecular Sciences, Arizona State University, Tempe, AZ 85281.ORCID 0000-0002-3522-3883
Chi-Nga ChowSchool of Molecular Sciences, Arizona State University, Tempe, AZ 85281.
Phoebe L DunnSchool of Life Sciences, Arizona State University, Tempe, AZ 85281.
Joshua D PodlevskySchool of Molecular Sciences, Arizona State University, Tempe, AZ 85281.
Tianxiang LiuSchool of Molecular Sciences, Arizona State University, Tempe, AZ 85281.
Khadiza AkhterSchool of Molecular Sciences, Arizona State University, Tempe, AZ 85281.ORCID 0000-0003-2752-9310
Julian J-L ChenSchool of Molecular Sciences, Arizona State University, Tempe, AZ 85281.ORCID 0000-0002-7253-2722

Funding

Biogenesis of mRNA-derived telomerase long noncoding RNAR01GM149864 · NIGMS · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI Julian J-L Chen · 2023 to 2026
$1.2M
HHS | NIH | National Institute of General Medical Sciences (NIGMS) GM149864NIGMS NIH HHS R01 GM149864NSF | BIO | Division of Molecular and Cellular Biosciences (MCB) MCB2046798
6 · The paper itself

Abstract

Telomerase elongates telomeres to maintain chromosome stability in most eukaryotes. Despite extensive studies across eukaryotic kingdoms, the telomerase holoenzyme in arthropods remains poorly understood. In this study, we purify the telomerase ribonucleoprotein complex from the lepidopteran insect

Indexed as

DNARNASpodopteraTelomeraseTelomereAnimalsDNARNATelomerasetelomerase RNAarthropodevolutionnoncoding RNARNA biogenesistelomere

Identifiers

PMID40020192
PMCPMC11892584

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.