ArticleMedicine2025
Research hotspots and trends of plumbagin: A bibliometric perspective.
Article in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- HMBOX1 plays a critical role in plumbagin-induced growth inhibition of hepatocellular carcinoma cells.Scientific reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Plumbagin is a biologically active naphthoquinone compound. Research related to plumbagin has gained popularity, evidenced by a gradual increase in publications. However, a bibliometric study in this field has yet to be conducted. Consequently, this study aims to evaluate the global scientific output of plumbagin research through bibliometric analysis, explore the status of research in this field over the past 15 years, and predict its future research hotspots. Visual analysis software, including CiteSpace, VOSviewer, and the R package 'bibliometrix', was employed to analyze all literature pertaining to plumbagin published between 2009 and 2024. Bibliometric records were sourced from the Web of Science Core Collection. This study analyzed a total of 2061 publications. China was found to have the largest number of publications, while the Council of Scientific & Industrial Research recorded the highest publication count in this field. Thomas and David D were identified as the authors with the most publications. The journal with the highest number of citations was J Biol Chem, and Padhye S was noted as the author with the highest citation count. In recent years, cancer treatment has emerged as the most closely related research topic concerning plumbagin, and keyword cluster analysis highlighted 'sarcoplasmic reticulum' as a prominent research keyword. Through quantitative and visual analysis of plumbagin, this study reveals that plumbagin research remains a valuable field. Anticancer treatment of plumbagin is identified as a future research direction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.