Evidence map›Paper›PMID 40020052›Full record

ArticleScience advances2025

Implantable wireless suture sensor for in situ tendon and ligament strain monitoring.

Guangmin Yang, Rongzan Lin, Haojie Li, Yuqiu Chen, Meiling Liu, Ziyang Luo, Kewei Wang, Jinying Tu, Yue Xu, Zixiao Fan and 4 more

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
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  7. [Research progress on flexible wearable sensors for health monitoring].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Guangmin YangSchool of Clinical Medicine, Tsinghua University, Beijing, China.ORCID 0000-0001-8751-8926
Rongzan LinSchool of Biomedical Engineering, Tsinghua University, Beijing 100084 China.ORCID 0000-0001-8564-3790
Haojie LiSchool of Biomedical Engineering, Tsinghua University, Beijing 100084 China.ORCID 0009-0005-8491-3441
Yuqiu ChenSchool of Biomedical Engineering, Tsinghua University, Beijing 100084 China.ORCID 0000-0002-1101-7348
Meiling LiuSchool of Biomedical Engineering, Tsinghua University, Beijing 100084 China.
Ziyang LuoSchool of Biomedical Engineering, Tsinghua University, Beijing 100084 China.
Kewei WangSchool of Biomedical Engineering, Tsinghua University, Beijing 100084 China.
Jinying TuSchool of Biomedical Engineering, Tsinghua University, Beijing 100084 China.ORCID 0009-0009-5740-9142
Yue XuSchool of Biomedical Engineering, Tsinghua University, Beijing 100084 China.ORCID 0009-0009-4066-0832
Zixiao FanSchool of Biomedical Engineering, Tsinghua University, Beijing 100084 China.ORCID 0009-0007-3464-7434
Yizhi ZhouSchool of Biomedical Engineering, Tsinghua University, Beijing 100084 China.
Yongwei PanSchool of Clinical Medicine, Tsinghua University, Beijing, China.ORCID 0000-0002-0456-9523
Zhe ZhaoSchool of Clinical Medicine, Tsinghua University, Beijing, China.ORCID 0000-0001-5959-9941
Ran LiuSchool of Biomedical Engineering, Tsinghua University, Beijing 100084 China.ORCID 0000-0002-6759-5681

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tendon and ligament ruptures are prevalent, and severe sports injuries require surgical repair. In clinical practice, monitoring of tissue strain is critical to alert severe postoperative complications such as graft reinjury and loosening. Here, we present a sensor system that integrates a strain sensor and communication coil onto surgical silk sutures, enabling in situ monitoring and wireless readout of tissue strains via surgical implantation. The flexible sensor shows excellent adaptability to soft tissues, providing a strain monitoring range of 0 to 10% with a minimum detection threshold of 0.25% and maintaining stability more than 300,000 stretching cycles. The wireless sensor could be integrated with complex structures in surgical scenarios involving lateral collateral ligament injury and anterior cruciate ligament reconstruction, enabling distinct responses to graft stretching, reinjury, and loosening. Animal experiments demonstrate that the sensor can acquire real-time, clinical-grade strain data while exhibiting high biocompatibility. The sensor system shows considerable potential in evaluating preclinical implant performance and monitoring implant-related surgical complications.

Indexed as

LigamentsProstheses and ImplantsSuturesTendonsWireless TechnologyAnimalsHumansMonitoring, PhysiologicStress, Mechanical

Identifiers

PMID40020052
PMCPMC11870077

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.