Evidence map›Paper›PMID 40019685›Full record

Observational studyJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2025

Safety and efficacy of atrial fibrillation ablation in kidney transplant patients.

Ahmad Keelani, Lorenzo Bartoli, Alessio Gasperetti, Sorin Popescu, Marco Schiavone, Anna Traub, Huong-Lan Phan, Marcel Feher, Thomas Fink, Vanessa Sciacca and 6 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ahmad KeelaniDepartment of Rhythmology, University Hospital Schleswig-Holstein - Campus Lübeck, Lübeck, Germany. A_kelani@hotmail.com.ORCID http://orcid.org/0000-0003-4811-4464
Lorenzo BartoliDepartment of Rhythmology, University Hospital Schleswig-Holstein - Campus Lübeck, Lübeck, Germany.ORCID http://orcid.org/0000-0002-8437-0222
Alessio GasperettiDepartment of Cardiology, Luigi Sacco University Hospital, Milan, Italy.
Sorin PopescuDepartment of Rhythmology, University Hospital Schleswig-Holstein - Campus Lübeck, Lübeck, Germany.
Marco SchiavoneDepartment of Clinical Electrophysiology & Cardiac Pacing, Centro Cardiologico Monzino, IRCCS, Milan, Italy.
Anna TraubDepartment of Rhythmology, University Hospital Schleswig-Holstein - Campus Lübeck, Lübeck, Germany.
Huong-Lan PhanDepartment of Rhythmology, University Hospital Schleswig-Holstein - Campus Lübeck, Lübeck, Germany.ORCID http://orcid.org/0000-0002-6867-914X
Marcel FeherDepartment of Rhythmology, University Hospital Schleswig-Holstein - Campus Lübeck, Lübeck, Germany.
Thomas FinkDepartment of Rhythmology, University Hospital Schleswig-Holstein - Campus Lübeck, Lübeck, Germany.
Vanessa SciaccaDepartment of Rhythmology, University Hospital Schleswig-Holstein - Campus Lübeck, Lübeck, Germany.
Martin NitschkeTransplant Center, University Hospital Schleswig-Holstein - Campus Lübeck, Lübeck, Germany.ORCID http://orcid.org/0000-0002-2716-7527
Julia VoglerDepartment of Rhythmology, University Hospital Schleswig-Holstein - Campus Lübeck, Lübeck, Germany.
Charlotte EitelDepartment of Rhythmology, University Hospital Schleswig-Holstein - Campus Lübeck, Lübeck, Germany.
Giovanni ForleoDepartment of Cardiology, Luigi Sacco University Hospital, Milan, Italy.
Christian-H HeegerDepartment of Rhythmology, University Hospital Schleswig-Holstein - Campus Lübeck, Lübeck, Germany.ORCID http://orcid.org/0000-0002-9014-8097
Roland R TilzDepartment of Rhythmology, University Hospital Schleswig-Holstein - Campus Lübeck, Lübeck, Germany.ORCID http://orcid.org/0000-0002-0122-7130

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionManaging atrial fibrillation in kidney transplant patients poses a challenge for both nephrologists and cardiologists. Data regarding the safety and efficacy of catheter ablation in this patient's cohort is scarce. METHODS AND

resultsIn this two-center prospective study, we included all consecutive kidney transplant patients who underwent atrial fibrillation ablation between April 2017 and March 2022. A 1:3 propensity score matching created a control group of non-transplant AF patients undergoing ablation. We included 16 kidney transplant patients and 48 matched controls. Ablation was successful in all patients. The periprocedural complication rate (6.3% in the kidney transplant group vs. 6.3% in the control group, p value = 1) did not differ between the two groups. One transplant patient experienced graft dysfunction after a complication. At 18 months, AF recurrence-fee rates were 69% in the transplant group and 70.1% in controls (p = 0.95). By the last follow-up, all transplant patients had discontinued antiarrhythmic drugs, while 19.6% of the patients in the control group were treated with antiarrhythmic drugs (p = 0.09). Kidney function in the transplant group remained stable (eGFR 32 [23.8, 40.5] ml/min/1.73 m

conclusionsThis study demonstrates that catheter ablation is a viable option for treating AF in kidney transplant patients, with comparable outcomes to non-transplanted individuals. Discontinuing antiarrhythmic drugs reduces drug interaction risks, but minimizing procedural complications remains critical to preserving graft function.

Indexed as

Atrial FibrillationCatheter AblationKidney TransplantationPostoperative ComplicationsFemaleHumansMaleMiddle AgedPropensity ScoreProspective StudiesTreatment OutcomeAtrial fibrillationCatheter ablationChronic kidney diseaseKidney transplant

Identifiers

PMID40019685
PMCPMC12317879

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.